Product Details
GLICLAZIDE 80 MG
Introduction : Gliclazide 80mg Tablet one of a group of medicines sulfonylureas.
It is an oral hypoglycaemic medicine (blood sugar lowering drug).
Gliclazide 80mg Tablet are used to keep blood sugar at the correct level in adults with non-insulin dependent
diabetes (type 2) when it is not controlled by diet, physical exercise and weight loss alone
Indication : Gliclazide 80mg Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It belongs to a group of medicines called sulfonylureas and helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.
Administration : Tablets are for oral use. Take your tablet(s) with a glass of water (and preferably at the same time each day). Swallow
your tablets whole. Do not chew them.
You must always eat a meal after taking your tablet(s).
Storage : Keep this medicine out of the sight and reach of children.
? Do not store above 250C. Store in the original package
Side Effects : Skin reactions such as rash, redness, itching, hives, angioedema, breathing difficulty, stomach upset
Safety Advice / Warnings : Do not take these Tablets if you: ? are allergic to Gliclazide or any of the other ingredients of this medicine (listed in section 6), to other medicines of the same group (sulfonylureas), to other related medicines (hypoglycaemic sulphonamides) ? have insulin-dependent diabetes (type 1) ? suffer from severe kidney or liver disease ? have ketone bodies and sugar in your urine (this may mean you have keto-acidosis) ? suffer from a diabetic pre-coma and coma ? are taking miconazole (a treatment for fungal infections) (see section ?Other medicines and Zicron ? Tablets?) ? are breast-feeding (see Pregnancy, breast-feeding and fertility)
Tablets are not recommended for use during pregnancy.
If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this
medicine.
You must not take this medicine while you are breast-feeding
Drinking alcohol is not recommended as it can alter the control of your diabetes in an unpredictable manner
References : https://www.drugs.com/uk/pdf/leaflet/1084506.pdf (Zircon product leaflet)
Bressler R & Johnson DG: Pharmacological regulation of blood glucose levels in non-insulin-dependent diabetes mellitus. Arch Intern Med 1997; 157:836-848.
Mechanism of Action : Gliclazide belongs to the sulfonylurea class of antidiabetic drugs, which work by stimulating insulin secretion from pancreatic beta cells.
Gliclazide binds to specific receptors on pancreatic beta cells, leading to the closure of ATP-sensitive potassium channels and subsequent depolarization of the cell membrane.
Therapeutic : Anti Diabetic