Product Details
VILDAGLIPTIN 50 MG
Introduction : VILDAGLIPTIN 50 MG tablet belongs to a group of medicines called ?oral antidiabetics?.
VILDAGLIPTIN 50 MG is used to treat adult patients with type 2 diabetes. It is used when diabetes cannot be controlled
by diet and exercise alone. It helps to control the level of sugar in the blood.
Type 2 diabetes develops if the body does not make enough insulin or if the insulin that the body
makes does not work as well as it should. It can also develop if the body produces too much glucagon.
Insulin is a substance which helps to lower the level of sugar in the blood, especially after meals.
Glucagon is a substance which triggers the production of sugar by the liver, causing the blood sugar
level to rise. The pancreas makes both of these substances.
Indication : VILDAGLIPTIN 50 MG tablet is indicated for the treatment of type 2 diabetes mellitus in adults as monotherapy or in combination with insulin.
Administration : Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist
if you are not sure
Storage : Store in original package; protect from moisture
Side Effects : Neurologic: Dizziness, Headache
Respiratory: Nasopharyngitis
Side effects may include tremor, headache, nausea, hypoglycemia, fatigue, constipation, asthenia, edema, and arthralgia
Safety Advice / Warnings : Talk to your doctor, pharmacist or nurse before taking Vidagliptin:
? if you have type 1 diabetes (i.e. your body does not produce insulin) or if you have a condition
called diabetic ketoacidosis.
? if you are taking an anti-diabetic medicine known as a sulphonylurea (your doctor may want to
reduce your dose of the sulphonylurea when you take it together with Jalra in order to avoid low
blood glucose [hypoglycaemia]).
? if you have moderate or severe kidney disease (you will need to take a lower dose of Jalra).
? if you are on dialysis.
? if you have liver disease.
? if you suffer from heart failure.
? if you have or have had a disease of the pancreas.
If you have previously taken vildagliptin but had to stop taking it because of liver disease, you should
not take this medicine.
Diabetic skin lesions are a common complication of diabetes. You are advised to follow the
recommendations for skin and foot care that you are given by your doctor or nurse. You are also
advised to pay particular attention to new onset of blisters or ulcers while taking Jalra. Should these
occur, you should promptly consult your doctor.
References : Product Information: Galvus oral tablets, vildagliptin oral tablets. Novartis Europharm Limited (per EMA), Camberley, United Kingdom, 2016.
Product Information: Xiliarx oral tablets, vildagliptin oral tablets. Novartis Europharm Limited (per EMA), Camberley, United Kingdom, 2015.
Product Information: Jalra oral tablets, vildagliptin oral tablets. Novartis Europharm Limited (per EMA), Camberley, United Kingdom, 2015.
Mechanism of Action : Vildagliptin is a complete dipeptidyl peptidase-4 inhibitor; such inhibition results in increased postprandial and fasting endogenous levels of the incretins glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide. Increased levels of these hormones improves glucose-dependent insulin secretion from pancreatic beta cells.
It works by making the pancreas produce more insulin and less glucagon. This helps to control the
blood sugar level. This medicine has been shown to reduce blood sugar, which may help to prevent
complications from your diabetes. Even though you are now starting a medicine for your diabetes, it is
important that you continue to follow the diet and/or exercise which has been recommended for you.
Therapeutic : Anti Diabetic