PREGABALIN 75 MG + NORTRIPTYLINE 10 MG

Product Details

PREGABALIN 75 MG + NORTRIPTYLINE 10 MG

the combination of Pregabalin and Nortriptyline provides synergistic pain relief and improved symptom control in neuropathic pain conditions such as diabetic neuropathy, postherpetic neuralgia, and neuropathic pain associated with spinal cord injury. The combination therapy of Pregabalin 75mcg and Nortriptyline 10mg tablet may provide comprehensive symptom management and improved quality of life for patients with fibromyalgia.

Pregabalin 75mcg and Nortriptyline 10mg tablet is primarily used for the management of neuropathic pain. Neuropathic pain arises from damage or dysfunction of the nervous system and can be chronic and debilitating. Pregabalin, an anticonvulsant medication, helps alleviate neuropathic pain by modulating calcium channels in the central nervous system, thereby reducing the release of neurotransmitters involved in pain signaling. Nortriptyline, a tricyclic antidepressant, is used off-label for the management of neuropathic pain, where its analgesic effects are believed to be mediated through its effects on neurotransmitter levels in the central nervous system.

Administer orally with or without food, as directed by the healthcare provider. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.

Store the medicine at room temperature, away from heat, moisture, and direct light.

Dizziness Drowsiness Dry mouth Constipation Blurred vision Weight gain Edema (swelling) Fatigue Headache Nausea Increased heart rate Urinary retention

Avoid use of this drug during pregnancy. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy and breastfeeding

Do not stop using this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. "The use of alcohol or other medicines that affect the CNS with pregabalin may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping This medicine may cause respiratory depression, a serious breathing problem that can be life-threatening, when used together with narcotic pain medicines. Check with your doctor right away Pregabalin may cause blurred vision, double vision, clumsiness, unsteadiness, dizziness, drowsiness, or trouble with thinking. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. If these side effects are especially bothersome, check with your doctor. patient to avoid drinking alcohol

Product Information: LYRICA(R) oral capsules, pregabalin oral capsules. Pfizer,Inc, New York, NY, 2007. Feltner DE, Crockatt JG, Dubovsky SJ, et al: A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder. J Clin Psychopharmacol 2003; 23(3):240-249." Product Information: Pamelor(TM) oral capsules, nortriptyline HCl oral capsules. Mallinckrodt Inc. (per FDA), Hazelwood, MO, 2014. Finnerup NB, Attal N, Haroutounian S, et al: Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 2015; 14(2):162-173.

Pregabalin: It is an anticonvulsant and analgesic medication that binds to calcium channels in the central nervous system, modulating the release of neurotransmitters involved in pain signaling. Pregabalin is effective in treating neuropathic pain associated with conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Nortriptyline: It is a tricyclic antidepressant (TCA) that inhibits the reuptake of serotonin and norepinephrine in the brain, leading to increased neurotransmitter levels. Nortriptyline is used off-label for the management of neuropathic pain, where its analgesic effects are believed to be mediated through its effects on neurotransmitter levels in the central nervous system.

analgesics and neurological agents.

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