Vildagliptin 50 Mg + Metformin Hydrochloride 500 Mg

Vildagliptin 50 mg: Vildagliptin is an oral antidiabetic medication that belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It helps lower blood sugar levels by inhibiting the enzyme DPP-4, which degrades incretin hormones that regulate insulin secretion. Metformin Hydrochloride 500 mg: Metformin is a biguanide antidiabetic drug that reduces glucose production in the liver, increases insulin sensitivity in peripheral tissues, and improves glucose uptake by muscles.

It is typically taken orally twice daily with meals or as directed by a healthcare professional. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

Store the medication at room temperature, away from moisture, heat, and direct sunlight.

Gastrointestinal disturbances such as nausea, vomiting, diarrhea, or abdominal discomfort fatigue, constipation,Headache Hypoglycemia (low blood sugar levels) when used in combination with insulin secretagogues or insulin Upper respiratory tract infections.

Acute or chronic metabolic acidosis including diabetic ketoacidosis Severe renal impairment.

Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems. Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. High blood sugar can be very serious and must be treated right away. It is important that you learn which symptoms you have in order to treat it quickly. Talk to your doctor about the best way to treat high blood sugar. Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk.

Product Information: Jalra oral tablets, vildagliptin oral tablets. Novartis Europharm Limited (per EMA), Camberley, United Kingdom, 2015. Product Information: Galvus oral tablets, vildagliptin oral tablets. Novartis Europharm Limited (per EMA), Camberley, United Kingdom, 2016. ""Product Information: GLUCOPHAGE(R) oral tablets, metformin HCl oral tablets. Bristol-Myers Squibb Company (per FDA), Princeton, NJ, 2017. Product Information: Metformin Juta oral tablet, metformin hydrochloride oral tablet. Juta Pharma GmbH (per AEMPS;Spain), Gutenbergstrasse 13, 24941 Flensburg, Germany, 2019.

Vildagliptin increases insulin secretion and suppresses glucagon release in a glucose-dependent manner by inhibiting the enzyme DPP-4, which leads to improved glycemic control. Metformin primarily works by reducing hepatic glucose production, enhancing insulin sensitivity in peripheral tissues, and improving glucose uptake by muscles, thereby lowering blood sugar levels.

Antidiabetic