METOPROLOL TARTRATE 25 MG + RAMIPRIL 2.5 MG

STRIP of 10 TAB.

Rx Prescription Required

METOPROLOL TARTRATE 25 MG + RAMIPRIL 2.5 MG

Manufacturer : TULBROS FORMULATIONSIn StockProduct Code : GMP0185MRP : ₹ 80.00 (Inclusive of all taxes)₹ 39.0051.25% Off Quantity : Add Request

Product Details

METOPROLOL TARTRATE 25 MG + RAMIPRIL 2.5 MG

Introduction :

Metoprolol Tartrate 25 Mg + Ramipril 2.5 Mg tablet is commonly prescribed for the management of hypertension (high blood pressure) and certain heart conditions in adults. It combines two different classes of medications: a beta-blocker (metoprolol succinate) and an ACE inhibitor (ramipril), to help control blood pressure and improve heart function. The importance of sustained-release (SR) formulations lies in their ability to provide a controlled release of medication over an extended period, SR formulations release the medication gradually into the bloodstream over an extended period, leading to more consistent blood levels throughout the day. This can result in smoother effects and a reduced risk of fluctuations.

Indication :

This combination medication is primarily prescribed for the treatment of hypertension (high blood pressure) in adults. It helps to lower blood pressure by reducing the heart rate and dilating blood vessels, thereby improving blood flow and reducing the workload on the heart. In some cases, Metoprolol Tartrate 25 Mg + Ramipril 2.5 Mg tablet may also be used for the management of heart failure. Both metoprolol succinate and ramipril have been shown to improve outcomes in patients with heart failure by reducing symptoms, preventing disease progression, and improving survival.

Administration :

It is typically taken orally once daily, with or without food. Swallow the extended-release capsule or tablet whole with a glass of water. Do not crush, break, or chew it.

Storage :

store at room temperature away from moisture and heat.

Mechanism of Action :

Metoprolol Succinate (SR): It belongs to the class of medications known as beta-blockers. It works by blocking the action of certain natural chemicals in the body, such as adrenaline, which play a role in regulating heart rate and blood pressure. By blocking these chemicals, metoprolol reduces the heart rate and workload on the heart, thereby lowering blood pressure and reducing the risk of cardiovascular events. Ramipril: This medication is an ACE inhibitor, which works by inhibiting the enzyme angiotensin-converting enzyme (ACE) in the body. ACE plays a role in the production of angiotensin II, a substance that causes blood vessels to constrict. By inhibiting ACE, ramipril helps to relax blood vessels, reduce blood pressure, and improve blood flow to the heart.

Therapeutic :

Cardiovascular Agent

Side Effects :

Common side effects of this medication combination may include dizziness, fatigue, headache, dry cough (associated with ramipril), nausea, diarrhea, and low blood pressure. Less common but more serious side effects may include electrolyte disturbances, kidney problems, and allergic reactions.

Contraindications :

Using this medicine while you are pregnant can harm your unborn baby. ,If you think you have become pregnant while using this medicine, tell your doctor right away.

Safety Advice / Warnings :

Patients should not abruptly stop taking this medication without consulting their healthcare provider, as sudden discontinuation may lead to rebound hypertension or other complications. This medicine may cause some people to become less alert than they are normally. If this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert while taking metoprolol Dizziness, lightheadedness, or even fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness. Patient should avoid using potassium-containing supplements or salts while taking this drug

References :

Product Information: Lopressor(R) oral tablets, metoprolol tartrate oral tablets. Validus Pharmaceuticals, LLC (per FDA), Parsippany, NJ, 2013. Product Information: ALTACE(R) oral capsules, ramipril oral capsules. King Pharmaceuticals, Inc, Bristol, TN, 2010. Heintz B, Verho M, Brockmeier D, et al: Multiple-dose pharmacokinetics of ramipril in patients with chronic congestive heart failure. J Cardiovasc Pharmacol 1993; 22(suppl 9):S36-S42 Drugs.com. Metoprolol Succinate and Ramipril. [Online] Available at: https://www.drugs.com/mtm/metoprolol-and-ramipril.html.

Disclaimer

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