Product Details
NEBIVOLOL 5 MG + HYDROCHLOROTHIAZIDE 12.5 MG
Introduction : This combination of Nebivolol 5 Mg + Hydrochlorothiazide 12.5 Mg medication is commonly prescribed for the treatment of hypertension (high blood pressure). Nebivolol is a beta-blocker that works by slowing down the heart rate and reducing the workload on the heart, while hydrochlorothiazide is a diuretic (water pill) that helps to lower blood pressure by increasing urine production and reducing fluid retention.
Indication : Nebivolol 5 Mg + Hydrochlorothiazide 12.5 Mg tablet primarily prescribed for the treatment of hypertension (high blood pressure) in adults. By combining a beta-blocker (Nebivolol) with a diuretic (Hydrochlorothiazide), this medication helps to lower blood pressure by reducing the heart rate, relaxing blood vessels, and promoting the excretion of excess salt and water from the body.
In some cases, Nebivolol 5 mg + Hydrochlorothiazide 12.5 mg may be used as part of the treatment regimen for heart failure. Heart failure is a condition where the heart is unable to pump blood effectively, Nebivolol helps to improve heart function by reducing the hearts workload and increasing its efficiency, while Hydrochlorothiazide helps to reduce fluid buildup in the body by increasing urine production.
Administration : It is typically taken orally once daily, with or without food.
The dosage should be determined by a healthcare professional
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Mechanism of Action : Nebivolol works by blocking the effects of certain natural substances in the body, such as epinephrine, on the heart and blood vessels. This helps to decrease heart rate and blood pressure.
Hydrochlorothiazide works by increasing the excretion of sodium and water by the kidneys, which reduces blood volume and subsequently lowers blood pressure.
Therapeutic : Antihypertensive
Side Effects : Dizziness
Fatigue
Headache
Nausea
Increased urination
Electrolyte imbalances (due to the diuretic effect of hydrochlorothiazide)
Hypotension (low blood pressure)
Bradycardia (slow heart rate)
Contraindications : Evidence demonstrated harmful infant effects when used during breastfeeding and pregnanacy
Safety Advice / Warnings : Avoid consuming alcohol while taking this medication, as it may worsen certain side effects such as dizziness and drowsiness.
This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems
This medication may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how this medication affects you.
Its important to regularly monitor your blood pressure while taking this medication and report any significant changes to your healthcare provider.
References : Product Information: BYSTOLIC(R) oral tablets, nebivolol oral tablets. Forest Pharmaceuticals Inc (per FDA), St Louis, MO, 2011.
Van de Water AR, Janssens W, Van Neuten J, et al: Pharmacological and hemodynamic profile of nebivolol, a chemically novel, potent, and selective beta-1#adrenergic antagonist. J Cardiovasc Pharmacol 1988; 11:552-563.