Product Details
NIFEDIPINE SR 20 MG
Introduction : Nifedipine SR 20mg tablet is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.These problems may be less likely to occur if blood pressure is controlled.
Nifedipine SR 20mg tablet is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.
Nifedipine SR 20mg tablet is available only with your doctors prescription.
Indication : Nifedipine SR 20mg tablet is used to prevent certain types of chest pain (angina). It may allow you to exercise more and decrease the frequency of angina attacks. Nifedipine belongs to a class of medications known as calcium channel blockers.
It works by relaxing blood vessels so blood can flow more easily.
Nifedipine SR 20mg tablet must be taken regularly to be effective. It should not be used to treat attacks of chest pain when they occur.
Administration : Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.
If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.
Do not crush, chew, or divide extended-release tablet
Storage : Protect from moisture or light and store below 30 degrees Celsius (C))
Mechanism of Action : NIFEdipine, a slow-calcium channel antagonist, selectively inhibits the transmembrane influx of calcium ions into cardiac muscle and vascular smooth muscle that is dependent upon for the contractile process, As an antihypertensive agent, NIFEdipine is a peripheral vasodilator causing arterial vasodilation, producing a reduction in peripheral vascular resistance
Therapeutic : Cardiovascular Agent
Side Effects : This drug may cause heartburn, nausea, or headache, weakness, swelling ankles/feet, constipation,
Contraindications : Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk.
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Safety Advice / Warnings : Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. These symptoms are more likely to occur when you begin taking this medicine, or when the dose is increased
Do not stop taking this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping completely.
Grapefruits and grapefruit juice may increase the effects of nifedipine by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine.
This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of the face, arms, hands, lower legs, or feet;
References : Product Information: PROCARDIA XL(R) oral extended release tablets, nifedipine oral extended release tablets. Pfizer Labs (per FDA), New York, NY, 2013.
Product Information: PROCARDIA(R) oral capsules, nifedipine oral capsules. Pfizer Labs (per FDA), New York, NY, 2013.
Product Information: ADALAT(R) CC oral extended release tablets, nifedipine oral extended release tablets. Schering Corporation, Whitehouse Station, NJ, 2010.