Ketoconazole 2% W/w + Cetrimide 0.5% W/w

Ketoconazole IP 2.0% W/W + Cetrimide 0.5% W/W cream cream is effective in treating various fungal skin infections, including: Tinea Corporis (Ringworm) , Tinea Cruris (Jock Itch), Tinea Pedis (Athlete's Foot), Tinea Versicolor, Cutaneous Candidiasis. Ketoconazole and Cetrimide combination cream may also be used for the management of seborrheic dermatitis, a common inflammatory skin condition characterized by red, itchy, and flaky skin on the scalp, face, and other areas of the body. The antifungal properties of ketoconazole help to control the proliferation of Malassezia yeast, which is associated with seborrheic dermatitis, while cetrimide provides antiseptic effects, reducing inflammation and preventing secondary infections.

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

Store the medicine at room temperature, away from heat, moisture, and direct light.

Skin irritation, Burning sensation, Itching, Redness, Dryness, Peeling of the skin.

Good health habits are also required for patients using the cream form of this medicine to help clear up your infection completely and to help make sure it does not return. Avoid wearing socks made from wool or synthetic materials (e.g., rayon or nylon). Instead, wear clean, cotton socks and change them daily or more often if your feet sweat a lot. Use a bland, absorbent powder (e.g., talcum powder) or an antifungal powder between the toes, on the feet, and in socks and shoes one or two times a day. It is best to use the powder between the times you use the cream. Avoid wearing underwear that is tight-fitting or made from synthetic materials (e.g., rayon or nylon). Instead, wear loose-fitting, cotton underwear.

Product Information: XOLEGEL(R) topical gel, ketoconazole topical gel. Aqua Pharmaceuticals, LLC (per FDA), San Antonio, TX, 2012. Heel RC, Brogden RN, Carmine A, et al: Ketoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infections. Drugs 1982; 23:1-36. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1576.

ketoconazole: It is an antifungal medication that works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting fungal cell membrane integrity, ketoconazole prevents the growth and replication of fungal organisms, ultimately leading to their eradication. Cetrimide: It is a quaternary ammonium compound with antiseptic properties. Cetrimide acts by disrupting the cell membranes of microorganisms, leading to their destruction. It may also help in preventing secondary bacterial infections associated with fungal skin infection

Anti fungal