Product Details
SPIRONOLACTONE 50 MG
Introduction : Spironolactone 50mg tablet is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Spironolactone 50mg tablet is also used to lessen the need for hospitalization for heart failure.
Spironolactone 50mg tablet is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome.
Spironolactone 50mg tablet is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).
This medicine is available only with your doctor?s prescription.
Indication : Spironolactone 50mg tablet is a diuretic that treats high blood pressure and heart failure. It can also reduce swelling related to heart, kidney or liver disease. It helps your kidneys remove more fluid and salt from your blood through your pee without losing too much potassium.
Spironolactone 50mg tablet treats high blood pressure and heart failure. It may also be used to reduce swelling related to heart, kidney, or liver disease. It helps your kidneys remove more fluid and salt from your blood through the urine without losing too much potassium. It belongs to a group of medications called diuretics.
Administration : Administer consistently with respect to food (ie, either with or without food)
Avoid use with potassium supplements and foods that contain high levels of potassium (eg, salt substitutes)
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Side Effects : Side effects may include diarrhea, nausea, vomiting, abdominal cramping, fever, leg cramps, lethargy, mental confusion, decreased libido, irregular menses, and rash
Contraindications : Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk.
Safety Advice / Warnings : Hyperkalemia (high potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have the following symptoms: stomach pain, confusion, difficulty with breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, or weakness or heaviness of the legs
Spironolactone may worsen kidney function in patients with low to no salt in their body or in those who take other blood pressure medicines
This medicine may also cause electrolyte imbalances (including low sodium, magnesium, and calcium in the blood, hypochloremic alkalosis) and an increase in your uric acid and blood sugar levels.
References : Product Information: CAROSPIR(R) oral suspension, spironolactone oral suspension. CMP Pharma, Inc (per manufacturer), Farmville, NC, 2017.
Product Information: Aldactone(R) oral tablets, spironolactone oral tablets. G.D. Searle (per FDA), New York, NY, 2014.
Product Information: Aldactone(R), spironolactone tablets, USP. Pharmacia Corp., Chicago, IL, 2003.
Mechanism of Action : Spironolactone is a renal competitive aldosterone antagonist. It inhibits the effect of aldosterone by competing for the aldosterone-dependent sodium-potassium exchange site in the distal tubule cells. This increases the secretion of water and sodium, while decreasing the excretion of potassium
Therapeutic : Cardiovascular Agent