Product Details
ACECLOFENAC 100 MG + PARACETAMOL 325 MG + SERRATIOPEPTIDASE 15 MG
Introduction : Serratiopeptidase 15mg is an enzyme with anti-inflammatory properties. It is believed to help reduce inflammation and potentially aiding in the resolution of certain types of inflammatory conditions.
Aceclofenac 100mg: Provides anti-inflammatory and analgesic effects, reducing pain associated with conditions such as osteoarthritis and rheumatoid arthritis.
Paracetamol 325mg: Aids in reducing fever, providing additional relief in conditions associated with elevated body temperature.
Indication : The combination of Aceclofenac 100 mg, Paracetamol 325 mg, and Serratiopeptidase 10 mg tablet is commonly used in certain regions for pain management and anti-inflammatory purposes.
Administration : It is typically taken orally, usually with food to reduce the risk of stomach upset.
Dosage should be determined by a healthcare professional based on the specific condition being treated and the patients individual needs.
Storage : Store the medication as directed on the packaging, typically at room temperature away from light and moisture.
Mechanism of Action : Aceclofenac is a nonsteroidal phenylacetic acid derivative related to diclofenac. Like other nonsteroidal antiinflammatory drugs (NSAIDS), aceclofenac is a prostaglandin synthetase (cyclooxygenase) inhibitor, which decreases prostaglandin and leukotriene production, therefore inhibiting the inflammatory process.
Paracetamol works by inhibiting the production of prostaglandins in the brain, which are involved in the perception of pain and regulation of body temperature. It is believed to exert its analgesic (pain-relieving) and antipyretic (fever-reducing) effects primarily by inhibiting the activity of the enzyme cyclooxygenase (COX), particularly COX-3, in the central nervous system.
Serratiopeptidase is an enzyme that exhibits anti-inflammatory and analgesic properties by breaking down and reducing the formation of abnormal proteins involved in inflammation and tissue damage.
Therapeutic : Anti Inflammatory
Side Effects : May cause stomach discomfort, nausea, or headache. If you have concerns, talk to your doctor.
Contraindications : Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Safety Advice / Warnings : NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use
Regular monitoring of liver function tests is advisable, especially with prolonged use of paracetamol.
Caution is advised in patients with pre-existing liver conditions.
Always take medications as prescribed by your healthcare provider and consult with them for any concerns or questions regarding your treatment.
This information is provided for general knowledge and does not replace professional medical advice.
Avoid alcohol consumption while taking diclofenac , paracetamol + serratiopeptidase, as it may increase the risk of stomach irritation and bleeding.
References : "Product Information: Aceclofenac oral tablets, aceclofenac oral tablets. Accord Healthcare Limited (per MHRA), Middlesex, United Kingdom, 2015.
https://www.medicines.org.uk/emc/product/2389/smpc#gref
Product Information: Paracetamol Aristogen 1000MG oral tablet, paracetamol 1000MG oral tablet. Aristo Pharma GmbH (per AEMPS;Spain), Wallenroder strabe 8-10, 13435 Berlin, Germany, 2019.
Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17