Nimesulide 100 Mg

Nimesulide 100 mg tablet is used to treat pain and fever. It provides relief from mild to moderate pain due to menstrual cramps and osteoarthritis. It decreases the intensity of pain signals to the brain and also prevents the release of substances called prostaglandins in the brain that cause pain and fever.

Nimesulide tablets should be taken orally with a full glass of water, preferably with or after meals to reduce the risk of gastrointestinal side effects. It is essential to swallow the tablet whole without chewing or crushing it.

Protect from moisture or light and store below 30 degrees Celsius (C).

Gastrointestinal disturbances (e.g., nausea, vomiting, dyspepsia, abdominal pain), Headache, Dizziness, Skin rash.

Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.

Use Nimesulide with caution in patients with a history of gastrointestinal ulcers, bleeding disorders, liver dysfunction, or renal impairment. Avoid concurrent use of Nimesulide with other NSAIDs or anticoagulant medications, as it may increase the risk of gastrointestinal bleeding. Long-term use of Nimesulide should be avoided, as it may increase the risk of adverse effects such as gastrointestinal ulcers, bleeding, and renal impairment. Discontinue Nimesulide and seek medical attention if any signs of allergic reactions or severe side effects occur, such as skin rash, swelling, difficulty breathing, or gastrointestinal bleeding.

Ward A & Brogden RN: Nimesulide. A preliminary review of its pharmacological properties and therapeutic efficacy in inflammation and pain states. Drugs 1988; 36:732-753. Pochobradsky MG, Mele G, Beretta A, et al: Post-marketing survey of nimesulide in the short-term treatment of osteoarthritis. Drugs Exp Clin Res 1991; 17:197-204.

Nimesulide exerts its pharmacological effects by inhibiting the enzyme cyclooxygenase (COX), thereby suppressing the synthesis of prostaglandins, which are mediators of inflammation, pain, and fever. By inhibiting prostaglandin synthesis, Nimesulide reduces inflammation, alleviates pain, and lowers fever.

Pain reliver.