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Tolvaptan 15 Mg Tablet
Medicine Product

Tolvaptan 15 Mg Tablet

Tolvaptan 15 mg Tablet contains Tolvaptan 15 mg, a selective vasopressin V2 receptor antagonist used to treat hyponatremia (low sodium levels) associated with conditions such as syndrome of inappropriate antidiuretic hormone secretion (SIADH), heart failure, and liver cirrhosis. It is also used in selected patients with autosomal dominant polycystic kidney disease (ADPKD) to slow disease progression.

₹ 259.00 46% Off

MRP: ₹ 478.95  *Inclusive of all taxes

USP: Rs. 64.75 / TAB

Pack Size STRIP OF 4 TAB
Composition TOLVAPTAN 15 MG
Product Code GMP2360
Views 12111

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Product Details

Indication of Tolvaptan 15 Mg Tablet
Clinically significant euvolemic hyponatremia Hypervolemic hyponatremia Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Hyponatremia associated with heart failure Hyponatremia associated with liver cirrhosis Autosomal dominant polycystic kidney disease (ADPKD) in eligible patients to slow disease progression
How To Use of Tolvaptan 15 Mg Tablet
Take the tablet exactly as prescribed by your doctor. It may be taken with or without food. Swallow the tablet whole with water. Maintain adequate access to drinking water, as the medicine increases urine output and thirst. Do not restrict fluids unless specifically instructed by your doctor. Regular monitoring of serum sodium, kidney function, liver function, and fluid status is required during treatment. Do not stop or adjust the dose without medical advice.
Storage of Tolvaptan 15 Mg Tablet
Store below 30°C.
Side Effects of Tolvaptan 15 Mg Tablet
Increased thirst Frequent urination Dry mouth Increased urine output Fatigue Constipation Dizziness
Contraindications of Tolvaptan 15 Mg Tablet
Are allergic to Tolvaptan or any ingredient in the tablet. Are unable to sense or respond to thirst. Have hypovolemic hyponatremia (low sodium due to volume depletion). Have anuria (absence of urine production). Have severe dehydration. Have severe liver impairment, unless the potential benefits outweigh the risks and your doctor recommends treatment.
Safety Advice of Tolvaptan 15 Mg Tablet
Use only under the supervision of a qualified healthcare professional. Regular monitoring of serum sodium, liver function tests, kidney function, and fluid balance is essential. Drink water whenever you feel thirsty to avoid dehydration. Inform your doctor immediately if you experience symptoms of liver injury such as loss of appetite, nausea, vomiting, jaundice, dark urine, or right upper abdominal pain. Avoid grapefruit or grapefruit juice, as it may increase Tolvaptan levels in the body. Inform your healthcare provider about all medicines you are taking, especially strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin), diuretics, and other medicines affecting sodium balance. Pregnancy and breastfeeding: Use only if clearly needed and prescribed by your doctor.
References of Tolvaptan 15 Mg Tablet
Tolvaptan Prescribing Information. Kidney Disease: Improving Global Outcomes (KDIGO). Clinical Practice Guidelines for Autosomal Dominant Polycystic Kidney Disease (ADPKD). European Society of Endocrinology (ESE). Clinical Practice Guideline on Hyponatremia.
Mechanism of Tolvaptan 15 Mg Tablet
Tolvaptan is a selective vasopressin V2 receptor antagonist. It blocks the action of arginine vasopressin (antidiuretic hormone, ADH) at V2 receptors in the collecting ducts of the kidneys, reducing water reabsorption and promoting the excretion of free water (aquaresis) without significant electrolyte loss. This increases serum sodium concentration in patients with hyponatremia. In ADPKD, inhibition of vasopressin signaling reduces cyclic AMP (cAMP)-mediated cyst growth and fluid secretion, helping slow the progression of kidney cyst enlargement and decline in kidney function.
Therapeutic of Tolvaptan 15 Mg Tablet
Vasopressin Receptor Antagonist (Aquaretic)
Manufacturer of Tolvaptan 15 Mg Tablet

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Comparison

Brand Genericart Medicine
Medicine VAPTAN TOLVAPTAN 15 MG TABLET
Composition TOLVAPTAN 15 MG TOLVAPTAN 15 MG
Company STEADFAST MEDISHIELD PVT LTD GENERICART MEDICINE
Price ₹ 1031.25 ₹ 259.00
You Save ₹ 772.25 (74.88% Less)

Disclaimer

At Genericart, our primary goal is to provide information that is thoroughly reviewed, accurate, and reliable. However, it is important to note that the content provided here should not be considered a substitute for professional medical advice. The information presented on our platform is intended for educational purposes only and may not cover all aspects of specific health conditions, medications, potential side effects, drug interactions, warnings, or alerts. We strongly encourage consulting with a qualified healthcare professional for advice and guidance regarding their health concerns and medication needs.

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