Cefpodoxime 200 Mg + Potassium Clavulanate 125 Mg

Take exactly as prescribed by your doctor. Usually taken once or twice daily, depending on the infection. Take with food to improve absorption and reduce stomach upset. Swallow the tablet whole with water. Complete the full course, even if symptoms improve earlier. Do not skip doses.

Store below 25–30°C. Keep in a dry place away from moisture and direct sunlight. Keep out of reach of children. Do not use after the expiry date.

Diarrhea Nausea or vomiting Abdominal pain Headache Skin rash

Use with caution in: Severe kidney impairment (dose adjustment required) History of gastrointestinal disease, especially colitis

Antacids may reduce absorption of this medicine. Avoid driving if dizziness occurs. this medicine should be used during pregnancy only if clearly needed and consulted with doctor

Product Information: Vantin(R) oral tablets, oral suspension, cefpodoxime proxetil oral tablets, oral suspension. Pharmacia & Upjohn Company (per FDA), New York, NY, 2013. Geddes AM: Cefpodoxime proxetil in the treatment of lower respiratory tract infections. Drugs 1991; 42(suppl 3):34-40. Greenfield RA: Symposium on antimicrobial therapy IV: the cephalosporins. J Okla State Med Assoc 1993; 86:7-12. Medscape Drug Monographs – Cefpodoxime, Clavulanate

Cefpodoxime is a third-generation cephalosporin that exerts bactericidal activity by binding to penicillin-binding proteins (PBPs) and inhibiting bacterial cell wall synthesis. Clavulanate irreversibly inhibits beta-lactamase enzymes, protecting cefpodoxime from hydrolysis and extending its spectrum against beta-lactamase–producing organisms. Potassium Clavulanate: It is a beta-lactamase inhibitor that helps overcome bacterial resistance to amoxicillin by protecting it from degradation by beta-lactamase enzymes produced by certain bacteria. Potassium clavulanate does not possess antibacterial activity on its own but enhances the activity of amoxicillin against beta-lactamase-producing bacteria.

Antibiotic