Product Details
WARFARIN SODIUM 2 MG
Introduction : WARFARIN SODIUM 2 MG is used for Prophylaxis and treatment of venous thrombosis , pulmonary embolism. It also helps in reduction of thromboembolic events such as stroke or systemic embolization after myocardial infarction.
Indication : WARFARIN SODIUM 2 MG is indicated in Prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE).
Warfarin is used to prevent blood clots from forming or growing larger in your blood and blood vessels.
Administration : The dosage may vary, and it should be determined by a healthcare professional based on the patients individual needs and response to treatment.
Storage : Store at a controlled room temperature between 15 and 30 degrees C (59 and 86 degrees F); protect from light and moisture
Side Effects : pain, swelling, or discomfort
headaches, dizziness, or weakness
bleeding from cuts takes a long time to stop
pink or brown urine
red or black stools
vomiting blood or material that looks like coffee grounds
Contraindications : Pregnancy, except in women with mechanical heart valves ? Hemorrhagic tendencies or blood dyscrasias
Recent or contemplated surgery of the central nervous system (CNS) or
eye, or traumatic surgery resulting in large open surfaces
? Bleeding tendencies associated with certain conditions
? Threatened abortion, eclampsia, and preeclampsia
? Unsupervised patients with potential high levels of non-compliance
? Spinal puncture and other diagnostic or therapeutic procedures with
potential for uncontrollable bleeding (4)
? Hypersensitivity to warfarin or any component of the product
? Major regional or lumbar block anesthesia
? Malignant hypertension
References : Label: JANTOVEN- warfarin sodium tablet
None Listed: The Warfarin Antiplatelet Vascular Evaluation Trial Investigators. Oral Anticoagulant and Antiplatelet Therapy and Peripheral Arterial Disease. N Engl J Med 2007; 357(3):217-227.
Product Information: COUMADIN(R) oral tablets, warfarin sodium oral tablets. Bristol-Myers Squibb Company (per manufacturer), Princeton, NJ, 2019.
Mechanism of Action : Warfarin sodium is an anticoagulant that works by blocking the regeneration of vitamin K(1) epoxide, thus inhibiting synthesis of vitamin K-dependent clotting factors which include factors 2, 7, 9 and 10, and the anticoagulant proteins C and S