Product Details
NEBIVOLOL HYDROCHLORIDE 5 MG
Introduction : Nebivolol 5mg tablet is used alone or together with other medicines to treat high blood pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Nebivolol 5mg tablet is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.
This medicine is available only with your doctors prescription.
Indication : Nebivolol 5 MG Tablet is a medicine used for lowering high blood pressure. It is also used to prevent other complications associated with increased blood pressure like heart attack, stroke (brain damage due to interrupted blood flow) and migraine (severe headache accompanied by nausea and light sensitivity). Nebivolol 5 MG Tablet is available in different doses (2.5mg, 5mg, 10mg, 20 mg). This medicine relaxes your blood vessels while also slowing the activity of your heart. As a result, your blood pressure drops, and it becomes easier for your heart to pump blood throughout your body.
Administration : May take with or without food
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Mechanism of Action : Nebivolol is a long-acting cardioselective beta-1 adrenoceptor antagonist without membrane stabilizing or intrinsic sympathomimetic activities . The mechanism of action of the antihypertensive response of nebivolol is not fully understood.
Therapeutic : Anti Hypertensive agent
Side Effects : Drug may cause headache, insomnia, diarrhea, nausea, chest pain, or peripheral edema
Contraindications : Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding
Safety Advice / Warnings : Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
This medicine may cause changes in your blood sugar levels. Also, this medicine may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests.
Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.
This medicine may cause some people to become less alert than they are normally. If this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert while taking nebivolol.
References : Product Information: BYSTOLIC(R) oral tablets, nebivolol oral tablets. Forest Pharmaceuticals Inc (per FDA), St Louis, MO, 2011.
AnonAnon: Nebivolol, in Phase III Profiles,, 1, Biomega Corp, Skokie, IL, 1992, pp 10-14.
Van de Water AR, Janssens W, Van Neuten J, et al: Pharmacological and hemodynamic profile of nebivolol, a chemically novel, potent, and selective beta-1#adrenergic antagonist. J Cardiovasc Pharmacol 1988; 11:552-563.