Ketoconazole 2.0% W/w Cream

This medicine is for use on the skin only. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

Store the medicine at room temperature, away from heat, moisture, and direct light.

Skin irritation, Burning sensation, Itching, Redness, Dryness, Peeling of the skin.

Evidence has demonstrated harmful infant effects when used during breastfeeding.

Good health habits are also required for patients using the cream form of this medicine to help clear up your infection completely and to help make sure it does not return. For patients using the cream for athlete's foot (tinea pedis; ringworm of the foot), the following instructions will help keep the feet cool and dry: Avoid wearing socks made from wool or synthetic materials (e.g., rayon or nylon). Instead, wear clean, cotton socks and change them daily or more often if your feet sweat a lot. Wear sandals or well-ventilated shoes (e.g., shoes with holes). Use a bland, absorbent powder (e.g., talcum powder) or an antifungal powder between the toes, on the feet, and in socks and shoes one or two times a day. It is best to use the powder between the times you use the cream. For patients using the cream for ringworm of the groin (tinea cruris; jock itch), the following instructions will help reduce irritation and will also help keep the groin area cool and dry: Avoid wearing underwear that is tight-fitting or made from synthetic materials (e.g., rayon or nylon). Instead, wear loose-fitting, cotton underwear. Use a bland, absorbent powder (e.g., talcum powder) or an antifungal powder on the skin. It is best to use the powder between the times you use ketoconazole cream.

Product Information: XOLEGEL(R) topical gel, ketoconazole topical gel. Aqua Pharmaceuticals, LLC (per FDA), San Antonio, TX, 2012. Heel RC, Brogden RN, Carmine A, et al: Ketoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infections. Drugs 1982; 23:1-36.

Ketoconazole the active ingredient in ketoconazole cream, is an antifungal medication that works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting fungal cell membrane integrity ketoconazole prevents the growth and replication of fungal organisms, ultimately leading to their eradication.

Anti-fungal