Product Details
PRAZOSIN EXTND RELEASE 2.5 MG
Introduction : Prazosin 2.5mg ER(extended release) is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries.
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Prazosin 2.5mg ER belongs to a class of medicines called antihypertensives. It works by relaxing the blood vessels so that blood passes through them more easily. This helps to lower blood pressure. Prazosin may also be used for other conditions as determined by your doctor.
This medicine is available only with your doctors prescription.
Indication : Prazosin 2.5mg ER(extended release) is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.Prazosin belongs to a class of medications called alpha blockers. It works by relaxing and widening blood vessels so blood can flow more easily.
Administration : Take this medicine exactly as directed by your doctor. Your doctor will tell you how much of this medicine to use and how often
Many patients who have high blood pressure will not notice any symptoms of the condition. In fact, many patients may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.
(Delayed-release tablets / Sustained release tablets) Swallow tablets whole, do not split, crush, or chew"
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Mechanism of Action : Prazosin hydrochloride is a quinazoline derivative which causes a reduction in total peripheral resistance and directly relaxes vascular smooth muscle, which may be related to postsynaptic alpha-adrenoceptor blockade
Therapeutic : Cardiovascular Agent
Side Effects : Dizziness; fast, irregular, pounding, or racing heartbeat or pulse; sleepiness
Contraindications : Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Safety Advice / Warnings : Dizziness, lightheadedness, or fainting may occur after you use this medicine, especially when you get up from a lying or sitting position. Getting up slowly may help lessen this problem. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning.
You may also have dizziness, lightheadedness, or fainting if you drink alcohol, stand for a long time, exercise or if the weather is hot. While you are taking this medicine, be careful to limit the amount of alcohol you drink. Drink plenty of fluids if you exercise or sweat more than usual while you are using this medicine.
Patient should not drink alcohol while taking this drug.
Prazosin may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy, drowsy, or are not alert.
References : Product Information: Minipress(R) oral capsules, prazosin HCl oral capsules. Pfizer Labs (per FDA), New York, NY, 2013.
Product Information: Minipress(R) oral capsules, prazosin hydrochloride oral capsules. Pfizer Labs, New York, NY, 2009.
Vincent J, Meredith PA, Reid JL, et al: Clinical pharmacokinetics of prazosin - 1985. Clin Pharmacokinet 1985; 10:144-154.