Product Details
TELMISARTAN 40 MG + CHLORTHALIDONE 6.25 MG
Introduction : This combination of TELMISARTAN 40 MG + CHLORTHALIDONE 6.25mg MG tablet is indicated to control the high blood presssure (hypertension)
Chlorthalidone 6.25mg is used alone or together with other medicines to treat high blood pressure (hypertension), it is also used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease,
Chlorthalidone is a diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps to lower blood pressure
Telmisartan 40mg is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, telmisartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Indication : Telmisartan 40mg works by relaxing and widening your blood vessels so your blood can flow more easily. This will lower your blood pressure. Chlorthalidone 6.25mg is known as a diuretic (water pill) which increases urine output thereby lowering blood pressure. If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective.
Administration : The usual recommended dosage of Telmisartan 40 mg + Chlorthalidone 6.25 mg is one tablet taken orally once daily.
It can be taken with or without food.
Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
Storage : Store the medication at room temperature, away from moisture and heat.
Keep it out of reach of children
Side Effects : Back Pain
Diarrhea
Increased Uric Acid Level in the Blood
Dizziness
Upper respiratory tract infection
Tiredness
Safety Advice / Warnings : Before taking chlorthalidone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.
Do report symptoms of potassium loss
Side effects may include hypotension, dizziness, and renal dysfunction
Do not drink alcohol while taking this drug, as this may aggravate hypotension.
References : Beermann B & Groschinsky-Grind MG: Clinical pharmacokinetics of diuretics. Clin Pharmacokinet 1980; 5:221-245.
Product Information: Chlorthalidone oral tablets, chlorthalidone oral tablets. Sun Pharmaceutical Industries Inc (per DailyMed), Cranbury, NJ, 2017.
"Product Information: MICARDIS(R) oral tablets, telmisartan oral tablets. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, 2009
Product Information: Telmisartan. Boehringer Ingelheim, US, 98.
Mechanism of Action : High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.
Therapeutic : Cardiovascular Agent