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Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Medicine Product

Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet

GLIBENCLAMIDE 5 MG + METFORMIN HYDROCHLORIDE 500 MG + PIOGLITAZONE HYDROCHLORIDE 15 MG

? 21.00 69.57% Off

MRP: ? 69.00  *Inclusive of all taxes

USP: Rs. 2.10 / TAB

Pack Size STRIP OF 10 TAB
Composition GLIBENCLAMIDE 5 MG + METFORMIN HYDROCHLORIDE 500 MG + PIOGLITAZONE HYDROCHLORIDE 15 MG
Product Code GMP1165
Views 4827

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Product Details

Indication of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
This medicine is used for the management of type 2 diabetes mellitus in adults, particularly when blood sugar levels cannot be adequately controlled with lifestyle modifications and single or dual therapy. It helps lower blood glucose levels and may reduce the risk of long-term complications such as heart disease, kidney damage, nerve damage, and vision problems associated with uncontrolled diabetes.
How To Use of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Take the tablet as prescribed by the physician. Usually taken once or twice daily with meals. Swallow the tablet with water. Follow dietary recommendations and regular physical activity for better diabetes control.
Storage of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Keep out of the reach and sight of children. Do not store above 25ºC. Keep in the original package or container supplied. Do not transfer them to another container. Do not use after the expiry date that is stated on the outer packaging.
Side Effects of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Nausea, Diarrhea, Weight gain, Headache, Hypoglycemia (low blood sugar) Fluid retention or swelling, Liver enzyme elevation, Vitamin B12 deficiency with long-term metformin use.
Contraindications of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Do not use this drug if: Known hypersensitivity to glibenclamide, metformin, pioglitazone, or related medicines Type 1 diabetes mellitus Diabetic ketoacidosis Severe kidney or liver impairment Severe heart failure
Safety Advice of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Monitor blood glucose levels regularly. This medicine is not recommended during pregnancy as there is positive evidence of fetal risk Watch for symptoms of low blood sugar, such as sweating, dizziness, or confusion. Inform your doctor if you have liver disease, heart disease, or kidney problems. Avoid Alcohol consumption as it may increase the risk of side effects. Regular monitoring of liver function and kidney function may be required.
References of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Panikar V, Chandalia HB, Joshi SR, et al. Beneficial effects of triple drug combination of pioglitazone with glibenclamide and metformin in type 2 diabetes mellitus patients on insulin therapy. J Assoc Physicians India. 2003;51:1061-4. FDA Drug Label – Glyburide (Glibenclamide), DailyMed Database. Product Information: Metformin Juta oral tablet, metformin hydrochloride oral tablet. Juta Pharma GmbH (per AEMPS;Spain), Gutenbergstrasse 13, 24941 Flensburg, Germany, 2019. Glibenclamide, Pioglitazone and Metformin Hydrochloride (SR) [Product Description]. Ahmedabad, Gujarat: TORRENT PHARMACEUTICALS LTD.; 2014. [Accessed 28th Sept. 2023]
Mechanism of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Glibenclamide stimulates insulin secretion from pancreatic β-cells by binding to the sulfonylurea receptor (SUR1) and inhibiting ATP-sensitive potassium channels, leading to depolarization and insulin release. Metformin reduces hepatic gluconeogenesis and improves peripheral insulin sensitivity through activation of AMP-activated protein kinase (AMPK). Pioglitazone acts as a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, enhancing insulin sensitivity in adipose tissue, skeletal muscle, and liver.
Therapeutic of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet
Anti Diabetic
Manufacturer of Glibenclamide 5 Mg + Metformin Hydrochloride 500 Mg + Pioglitazone Hydrochloride 15 Mg Tablet

ADDII BIOTECH PVT. LTD.

VILL. KAUNDI, PO THANA, THE. BADDI DIST- SOLAN H.P., THANA, SIRMAURI TAL (19), SIRMAUR, HIMACHAL PRADESH, 173205, INDIA

Disclaimer

At Genericart, our primary goal is to provide information that is thoroughly reviewed, accurate, and reliable. However, it is important to note that the content provided here should not be considered a substitute for professional medical advice. The information presented on our platform is intended for educational purposes only and may not cover all aspects of specific health conditions, medications, potential side effects, drug interactions, warnings, or alerts. We strongly encourage consulting with a qualified healthcare professional for advice and guidance regarding their health concerns and medication needs.

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