Telmisartan 40 Mg + Amlodipine 5 Mg + Hydrochlorothiazide 12.5 Mg

Typically, one tablet is taken orally once daily, with or without food. It's essential to follow the dosage instructions provided by your healthcare provider and not to exceed the prescribed dose. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate.

Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children.

Common side effects may include dizziness, headache, fatigue, electrolyte disturbances (such as low potassium levels), increased urination, and dehydration.

Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding. Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.

This medication may cause dizziness or lightheadedness, especially during the first few days of treatment or when standing up quickly from a sitting or lying position. Use caution when driving or operating machinery until you know how the medication affects you. Avoid consuming alcohol while taking this medication, as it may potentiate the blood pressure-lowering effects and increase the risk of side effects. Inform your healthcare provider about any other medications, supplements, or medical conditions you have before starting treatment with telmisartan/hydrochlorothiazide. Severe sweating, diarrhea, or vomiting may cause dehydration and cause you to feel lightheaded. Tell your doctor if you have severe diarrhea or vomiting. To prevent dehydration, drink plenty of fluids unless your doctor tells you not to.

Product Information: MICARDIS(R) oral tablets, telmisartan oral tablets. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, 2009. Product Information: Telmisartan. Boehringer Ingelheim, US, 98. ""Product Information: Hydrochlorothiazide Aurovitas oral tablet, hydrochlorothiazide oral tablet. Aurovitas Spain, SAU (per AEMPS;Spain), Avda, De Burgos, 28036 Madrid, Spain, 2019. Product Information: Hydrochlorothiazide oral tablets, hydrochlorothiazide oral tablets. Accord Healthcare Inc (per DailyMed), Durham, NC, 2020. Amlodipine besylate [FDA Label]. New York, NY: Pfizer Labs.; 1987 [revised May 2011]. [Accessed 14 Mar. 2019] (online) Available from:External Link""

Telmisartan: Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to its receptors, leading to vasodilation and lowering of blood pressure Hydrochlorothiazide increases urine production by inhibiting the reabsorption of sodium and chloride ions in the kidneys, resulting in the removal of excess salt and water from the body and lowering blood volume and pressure. Amlodipine is a dihydropyridine calcium channel blocker that exerts its effect by blocking the transmembrane influx of calcium ions into cardiac and vascular smooth muscles. It also reduces peripheral vascular resistance and lowers blood pressure by acting directly on vascular smooth muscle. Its therapeutic effect on angina may be through a decrease in peripheral resistance (exertional angina) and inhibition of coronary spasm (vasospastic angina).

Cardiovascular Agent