Product Details
OMEPRAZOLE 20 MG
Introduction : Omeprazole 20mg capsules is used to treat certain conditions where there is too much acid in the stomach.
Omeprazole 20mg capsules are used to treat gastric and duodenal ulcers, erosive esophagitis, and gastroesophageal reflux disease (GERD). GERD is a condition where the acid in the stomach washes back up into the esophagus. Sometimes omeprazole is used in combination with antibiotics (eg, amoxicillin, clarithromycin) to treat ulcers associated with the infection caused by the H. pylori bacteria.
Omeprazole20mg capsules is also used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid.
Omeprazole is also used to treat dyspepsia, a condition that causes sour stomach, belching, heart burn, or indigestion.
This medicine is available both over-the-counter (OTC) and with your doctors prescription.
Indication : OMEPRAZOLE 20 MG capsules is used to treat certain stomach and esophagus problems (such as acid reflux). It works by decreasing the amount of acid your stomach makes. This medication relieves symptoms such as heartburn, difficulty swallowing, and cough. It helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.
In addition, omeprazole is used to prevent upper gastrointestinal tract bleeding in seriously ill patients.
Omeprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.
Administration : Should be taken at least 30 minutes before meals.
(Delayed-release tablets) Swallow tablets whole, do not split, crush, or chew
Storage : Store at room temperature away from moisture and heat.
Side Effects : side effects may include headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, arthralgia, rash, and fever
Contraindications : Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Safety Advice / Warnings : Taking this medicine for a long time may make it harder for your and your childs body to absorb vitamin B12. Tell your doctor if you have concerns about this.
References : Berardi RR & Welage LS: Proton-pump inhibitors in acid-related diseases.. Am J Health-Syst Pharm 1998; 55:2289-98.
Product Information: PRILOSEC(R) oral delayed-release capsules, omeprazole oral delayed-release capsules. AstraZeneca LP (per FDA), Wilmington, DE, 2016.
Mechanism of Action : Omeprazole is a selective and irreversible [30] proton pump inhibitor. Omeprazole suppresses gastric acid secretion by specific inhibition of the hydrogen?potassium adenosinetriphosphatase (H +, K +-ATPase) enzyme system found at the secretory surface of parietal cells . It inhibits the final transport of hydrogen ions (via exchange with potassium ions) into the gastric lumen. Since the H +, K +-ATPase enzyme system is regarded as the acid (proton) pump of the gastric mucosa, omeprazole is known as a gastric acid pump inhibitor.
Therapeutic : Gastric Acid Secretion Inhibitor