Product Details
OLMESARTAN MEDOXOMIL 40 MG + HYDROCHLOROTHIAZIDE 12.50 MG
Introduction : Olmesartan 40mg and hydrochlorothiazide 12.5mg tablets combination is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.
Olmesartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, olmesartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
Hydrochlorothiazide is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure.
This medicine is available only with your doctors prescription.
Indication : Olmesartan 40mg and hydrochlorothiazide 12.5mg tablet is primarily prescribed for the treatment of hypertension (high blood pressure) in adults. It is particularly beneficial for individuals whose blood pressure is not adequately controlled with monotherapy or who require combination therapy to achieve target blood pressure levels.
By lowering blood pressure, this medication helps reduce the risk of cardiovascular events such as heart attacks, strokes, and other complications associated with hypertension.
Administration : This medicine may be taken with or without food.
In addition to taking this medicine, treatment for your high blood pressure may include weight control and a change in the foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you.
Storage : Protect from moisture or light and store below 30 degrees Celsius (C))
Mechanism of Action : Olmesartan medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby relaxing blood vessels and lowering blood pressure.
Hydrochlorothiazide is a thiazide diuretic that works by increasing the excretion of sodium and water from the body, leading to reduced blood volume and decreased blood pressure.
Therapeutic : Angiotensin II Receptor Antagonist/Thiazide Combination
Side Effects : Side effects may include nausea, hyperuricemia, dizziness, and upper respiratory infection,Back pain; body aches or pain; chills; cough;fever; headache;runny or stuffy nose; sneezing; sore throat
Contraindications : Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Evidence has demonstrated harmful infant effects when used during breastfeeding
Safety Advice / Warnings : Dizziness, lightheadedness, or fainting may also occur, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to the medicine before you drive, use machines, or do other things that could be dangerous if you are dizzy. If you feel dizzy, sit for a few moments before standing.
Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea that does not stop. These conditions may cause you to lose too much water or salt and lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather.
Severe, chronic diarrhea with weight loss may develop months to years after taking this medicine. Tell your doctor right away if you have these symptoms.
Check with your doctor right away if blurred vision, difficulty with reading, eye pain, or any other vision change occurs with this medicine. This could be a sign of a serious eye problem.
This medicine may affect blood sugar levels. Diabetic patients may notice a change in the results of blood or urine sugar tests. Talk to your doctor if you have any questions.
References : Product Information: BENICAR HCT(R) oral tablets, olmesartan medoxomil hydrochlorothiazide oral tablets. Daiichi Sankyo, Inc (per FDA), Parsippany, NJ, 2020.
Product Information: BENICAR HCT(TM) oral tablet, hydrochlorothiazide/olmesartan medoxomil oral tablet. Sankyo Pharma Inc, Parsippany, NJ, 2004.