Product Details
GLIMEPIRIDE 0.5 MG
Introduction : Glimepiride 0.5mg tablet is used to treat high blood sugar levels caused by type 2 diabetes. It may be used alone, or in combination with insulin or another oral medicine such as metformin. In type 2 diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly.
Using this medicine will help lower blood sugar when it is too high and help restore the way you use food to make energy. Some people can control type 2 diabetes with diet alone or diet and exercise.
Following a specially planned diet and exercising will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of glimepiride you take must be balanced against the amount and type of food you eat and the amount of exercise you do.
If you change your diet, your exercise, or both, you will want to test your blood sugar to find out if it is too low. Your doctor will teach you what to do if this happens.
This medicine is available only with your doctors prescription.
Indication : Glimepiride 0.5mg tablet is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Proper control of diabetes may also lessen your risk of a heart attack or stroke. Glimepiride belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your bodys natural insulin.
Administration : You should take this medicine with breakfast or the first main meal of the day.
The dose of this medicine will be different for different patients. Follow your doctors orders or the directions on the label
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Side Effects : Hypoglycemia
Nausea
, Dizziness
, Headache
Skin reactions
Contraindications : Avoid preganancy and lactation (breastfeeding) while consuming this medicines
Safety Advice / Warnings : Alcohol?Drinking alcohol may cause severe low blood sugar.
counseling on contraception and pregnancy may be needed because of the problems that can occur in patients with diabetes during pregnancy.
Travel?Keep your recent prescription and your medical history with you. Be prepared for an emergency as you would normally. Make allowances for changing time zones and keep your meal times as close as possible to your usual meal times.
Too much glimepiride can cause low blood sugar (hypoglycemia) when it is used under certain conditions. Symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people may feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly.
If symptoms of low blood sugar occur, eat glucose tablets or gel, corn syrup, honey, or sugar cubes; or drink fruit juice, non-diet soft drink, or sugar dissolved in water.
This medicine may cause dizziness, drowsiness, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert or able to think well.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
References : Product Information: AMARYL(R) oral tablets, glimepiride oral tablets . Sanofi-Aventis U.S. LLC (per FDA), Bridgewater, NJ, 2016.
Badian M, Korn A, Lehr KH, et al: Determination of the absolute bioavailability of glimepiride (HOE 490), a new sulphonylurea. Int J Clin Pharmacol Ther Toxicol 1992; 30(11):481-482.
Product Information: glimepiride oral tablets, glimepiride oral tablets. Accord Healthcare, Inc. (per DailyMed), Durham, NC, 2015.
Mechanism of Action : Glimepiride is a sulfonylurea; it stimulates insulin release from functioning pancreatic beta cells by binding to the sulfonylurea receptor, leading to closure of the ATP-sensitive potassium channel, which results in insulin release and a subsequent decrease in blood glucose
Therapeutic : Anti Diabtetic