Product Details
SODIUM VALPROATE 200 MG + VALPROIC ACID 87 MG CR
Introduction : Sodium Valproate 200 Mg + Valproic Acid 87 Mg CR (controlled release) tablet is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves and hence, prevents seizures or fits.
It is used to treat certain types of seizures (epilepsy). This medicine is an anticonvulsant that works in the brain tissue to stop seizures.
this tablet is also used to treat the manic phase of bipolar disorder (manic-depressive illness), and helps prevent migraine headaches.
This medicine is available only with your doctors prescription.
Indication : This medication is typically prescribed for the treatment of seizure disorders, including epilepsy. It helps control seizures by stabilizing electrical activity in the brain.
Sodium Valproate 200 Mg + Valproic Acid 87 Mg CR (controlled release) tablet slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
Administration : Swallow the delayed-release capsules or oral capsules whole with a full glass of water. Do not split, crush, or chew it. You may take this medicine with food to decrease stomach upset.
Storage : Store the mediciner at room temperature, away from heat, moisture, and direct light.
Side Effects : Side effects may include abdominal pain, alopecia, amblyopia/blurred vision, amnesia, anorexia, asthenia, nausea, and insomnia
Contraindications : Avoid use of this drug during pregnancy , Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk.
Safety Advice / Warnings : Using this medicine while you are pregnant (especially during the first 3 months of pregnancy) can harm your unborn baby and cause serious unwanted effects
Valproic acid may cause serious allergic reactions affecting multiple body organs (eg, liver or kidney).
Valproic acid may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally.
Do not stop using this medicine without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping completely.
patient to avoid activities requiring mental alertness or coordination until drug effects are realized, as drug may cause drowsiness
References : Klotz U & Antonin KH: Pharmacokinetics and bioavailability of sodium valproate. Clin Pharmacol Ther 1977; 21:736-743.
Product Information: Depakine Chrono oral tablet, sodium valproate and valproic acid oral tablet. Sanofi-Aventis France (per SFDA; Saudi Arabia), 2018.
Mechanism of Action : Sodium Valproate and Valproic Acid: They work by increasing the levels of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits brain activity. By enhancing GABA levels, these medications help to stabilize electrical activity in the brain, thereby reducing the likelihood of seizures.
Therapeutic : Anti convulsant