Product Details
THYROXINE SODIUM 12.5 MCG
Introduction : Thyroxine Sodium 12.5mcg tablet is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. This medicine is also used to help decrease the size of enlarged thyroid glands (also called a goiter).
Thyroxine Sodium 12.5mcg tablet belongs to a class of medications called hormones. It works by replacing thyroid hormone that is normally produced by the body.
Without thyroid hormone, your body cannot function properly, which may result in poor growth, slow speech, lack of energy, excessive tiredness, constipation, weight gain, hair loss, dry, thick skin, increased sensitivity to cold, joint and muscle pain, heavy or irregular menstrual periods, and depression. When taken correctly, Thyroxine Sodium reverses these symptoms.
This medicine is available only with your doctors prescription.
Indication : Hypothyroidism: Used for the treatment of an underactive thyroid gland, a condition known as hypothyroidism.
Levothyroxine is a synthetic version of thyroxine. You take Thyroxine Sodium tablets to replace the thyroxine that your thyroid gland cannot produce and prevent the symptoms of hypothyroidism.
Administration : Take the capsule or tablet in the morning on an empty stomach, at least 30 to 60 minutes before eating breakfast.
Swallow the tablet whole. Do not cut, chew, or crush it.
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Side Effects : Feeling sick (nausea)
Being sick (vomiting)
Diarrhoea
Headaches
skin rash, angioedema, abdominal pain,
Safety Advice / Warnings : Thyroxine Sodium should not be used for the treatment of obesity or for the purpose of losing weight. This medicine is not effective for weight reduction. If taken in large amounts, Thyroxine Sodium may cause serious unwanted effects.
Hypothyroidism can sometimes cause infertility in men and women. Thyroxine Sodium should not be used for the treatment of infertility unless it is caused by hypothyroidism.
For patients with diabetes: It is very important that you keep track of your blood or urine sugar levels as instructed by your doctor. Check with your doctor right away if you notice any changes in your sugar levels.
If you think you have become pregnant while using this medicine, tell your doctor right away. You may need a larger dose of Thyroxine Sodium while you are pregnant.
Women who are post-menopausal or who use this medicine for a long time may have some bone loss, which could lead to osteoporosis. Talk with your doctor if you have questions or concerns about this.
Do not eat grapefruit or drink grapefruit juice while you are using this medicine.
References : Product Information: Thyroxine Sodium sodium intravenous injection, Thyroxine Sodium sodium intravenous injection. Fresenius Kabi USA LLC (per FDA), Lake Zurich, IL, 2019.
https://www.nhs.uk/medicines/Thyroxine Sodium/
Product Information: NOVOTHYROX(R) oral tablets, Thyroxine Sodium sodium oral tablets. Merck KGaA, Darmstadt, Germany, 2008.
Micromedex Drug information Database
Mechanism of Action : Thyroid hormones exert their physiologic actions through control of DNA transcription and protein synthesis. Triiodothyronine (T3) and Thyroxine Sodium (T4) diffuse into the cell nucleus and bind to thyroid receptor proteins attached to DNA. This hormone nuclear receptor complex activates gene transcription and synthesis of messenger RNA and cytoplasmic proteins. The physiological actions of thyroid hormones are produced predominantly by T3, the majority of which (approximately 80%) is derived from T4 by deiodination in peripheral tissues
Therapeutic : Thyroid Supplement