NORTRIPTYLINE 10 MG + METHYLCOBALAMIN 1500 MCG + PREGABALIN 75 MG

STRIP of 10 TAB.

Rx Prescription Required

NORTRIPTYLINE 10 MG + METHYLCOBALAMIN 1500 MCG + PREGABALIN 75 MG

Manufacturer : LIFE MAX CANCERIn StockProduct Code : GMP0326MRP : ₹ 195.00 (Inclusive of all taxes)₹ 103.0047.18% Off Quantity : This Product is not for Online Sale, You can purchase it from Physical Store.

Product Details

NORTRIPTYLINE 10 MG + METHYLCOBALAMIN 1500 MCG + PREGABALIN 75 MG

Introduction :

This combination medication is commonly prescribed for the management of neuropathic pain. Neuropathic pain arises from damage or dysfunction of the nervous system and can be chronic Pregabalin 75 Mg + Nortriptyline Hcl 10 Mg + Methylcobalamine 1500 Mcg tablet provides comprehensive pain relief and improved symptom control in neuropathic pain conditions such as diabetic neuropathy, postherpetic neuralgia, and neuropathic pain associated with spinal cord injury. Peripheral neuropathy is a common complication of conditions such as diabetes mellitus and vitamin B12 deficiency, characterized by damage to the peripheral nerves, resulting in symptoms such as numbness, tingling, burning sensations, and pain in the extremities. Pregabalin, Nortriptyline, and Methylcobalamin combination therapy is effective in managing peripheral neuropathy symptoms

Indication :

Pregabalin 75 Mg + Nortriptyline Hcl 10 Mg + Methylcobalamine 1500 Mcg tablet is typically prescribed for the management of neuropathic pain and related neurological symptoms.

Administration :

Administer orally with or without food, as directed by the healthcare provider. Swallow the tablet whole with a glass of water; do not crush, chew, or break it.

Storage :

Store the medicine at room temperature, away from heat, moisture, and direct light.

Side Effects :

Dizziness Drowsiness Dry mouth Constipation Blurred vision Weight gain Edema (swelling) Fatigue Headache Nausea Increased heart rate Urinary retention

Contraindications :

Avoid use of this drug during pregnancy. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy and breastfeeding

Safety Advice / Warnings :

Use caution when driving or operating machinery, as this medication may cause dizziness or drowsiness. "The use of alcohol or other medicines that affect the CNS with pregabalin may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping This medicine may cause respiratory depression, a serious breathing problem that can be life-threatening, when used together with narcotic pain medicines. Check with your doctor right away Pregabalin may cause blurred vision, double vision, clumsiness, unsteadiness, dizziness, drowsiness, or trouble with thinking. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. If these side effects are especially bothersome, check with your doctor. Do not suddenly stop taking pregabalin without checking first with your doctor. patient to avoid drinking alcohol Extended-release tablets: If a dose is missed with the evening meal, instruct patient to take before bedtime after a snack or the following morning after a meal. "

References :

Product Information: LYRICA(R) oral capsules, pregabalin oral capsules. Pfizer,Inc, New York, NY, 2007. Yoshioka K & Tanaka K: Effect of methylcobalamin on diabetic neuropathy as assessed by power spectral analysis of heart rate variations. Horm Metab Res 1995; 27(1):43-44. Product Information: Pamelor(TM) oral capsules, nortriptyline HCl oral capsules. Mallinckrodt Inc. (per FDA), Hazelwood, MO, 2014. Finnerup NB, Attal N, Haroutounian S, et al: Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol 2015; 14(2):162-173.

Mechanism of Action :

Pregabalin: It is an anticonvulsant and analgesic medication that binds to calcium channels in the central nervous system, modulating the release of neurotransmitters involved in pain signaling. Pregabalin is effective in treating neuropathic pain associated with conditions such as diabetic neuropathy, postherpetic neuralgia, and fibromyalgia. Methylcobalamin: It is a form of vitamin B12 that plays a crucial role in nerve function and regeneration. Methylcobalamin helps maintain the health of nerve cells and is used in the treatment of peripheral neuropathy, a common complication of conditions such as diabetes and vitamin B12 deficiency. Nortriptyline: It is a tricyclic antidepressant (TCA) that inhibits the reuptake of serotonin and norepinephrine in the brain, leading to increased neurotransmitter levels. Nortriptyline is used off-label for the management of neuropathic pain, where its analgesic effects are believed to be mediated through its effects on neurotransmitter levels in the central nervous system.

Therapeutic :

analgesics and neurological agents.

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