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Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Medicine Product

Sacubitril 49 Mg + Valsartan 51 Mg Tablet

Sacubitril 49 mg + Valsartan 51 mg Tablet is a combination medicine used to treat chronic heart failure with reduced ejection fraction (HFrEF). It helps improve heart function, reduces hospitalization due to heart failure, and lowers the risk of cardiovascular death.

₹ 190.00 79.70% Off

MRP: ₹ 936.00  *Inclusive of all taxes

USP: Rs. 13.57 / TAB

Pack Size STRIP OF 14 TAB
Composition SACUBITRIL 49 MG + VALSARTAN 51 MG
Product Code GMP1636
Views 6630

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Product Details

Indication of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Sacubitril 49 Mg + Valsartan 51 Mg death in patients with long-lasting (chronic) heart failure. It is generally given along with other heart failure medications.
How To Use of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Administer orally with or without food. Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
Storage of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Store the medicine at room temperature, away from heat, moisture, and direct light. Keep out of the reach of children.
Side Effects of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Side effects may include Hyperkalemia (high potassium levels), cough, dizziness, or renal failure, Fatigue, Cough, Increased serum creatinine levels.
Contraindications of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Avoid use of this drug during pregnancy. Evidence has demonstrated risks when used during pregnancy and breastfeeding.
Safety Advice of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
"Do not take this medicine for at least 36 hours before or after you take an ACE inhibitor medicine. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. Ask your doctor before you use medicines, supplements, or salt substitutes that contain potassium. Use caution in patients with renal impairment or on dialysis, as the risk of hyperkalemia may be increased. Monitor blood pressure, renal function, and electrolytes regularly during treatment.
References of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Product Information: ENTRESTO(TM) oral tablets, sacubitril valsartan oral tablets. Novartis Pharmaceuticals Corporation (per Manufacturer), East Hanover, NJ, 2015. Flarakos J, Du Y, Bedman T, et al: Disposition and metabolism of [(14)C] sacubitril/valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects. Xenobiotica 2016; 46(11):986-1000.
Mechanism of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
Sacubitril: It is a neprilysin inhibitor. Neprilysin is an enzyme responsible for breaking down natriuretic peptides, which play a role in regulating blood pressure and fluid balance. By inhibiting neprilysin, sacubitril increases the levels of natriuretic peptides, resulting in vasodilation and natriuresis, which helps reduce blood pressure and improve heart failure symptoms. Valsartan: It is an angiotensin II receptor blocker (ARB). Valsartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby reducing blood pressure and workload on the heart.
Therapeutic of Sacubitril 49 Mg + Valsartan 51 Mg Tablet
angiotensin receptor-neprilysin inhibitors (ARNIs).
Manufacturer of Sacubitril 49 Mg + Valsartan 51 Mg Tablet

ADDII BIOTECH PVT. LTD.

VILL. KAUNDI, PO THANA, THE. BADDI DIST- SOLAN H.P., THANA, SIRMAURI TAL (19), SIRMAUR, HIMACHAL PRADESH, 173205, INDIA

Comparison

Generic Medicine Brand
Medicine SACUBITRIL 49 MG + VALSARTAN 51 MG TABLET VALSAC 100
Composition SACUBITRIL 49 MG + VALSARTAN 51 MG SACUBITRIL 49 MG + VALSARTAN 51 MG
Price ₹ 190.00 ₹ 1443.75
You Save ₹ 1,253.75 (86.84% Less)

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