Product Details
TICAGRELOR TABLETS 90 MG
Introduction : Ticagrelor 90mg tablet is used alone or together with aspirin to lessen the chance of heart attack or stroke in patients with acute coronary syndrome (ACS) or a history of heart attack. Acute coronary syndrome is a condition where the blood flow to the heart is blocked. It is also used to reduce the risk of blood clots in patients who have received stents to treat ACS.
Ticagrelor 90mg tablet is also used alone or together with aspirin to lessen the chance of first heart attack or stroke in patients with coronary artery disease (CAD) who are at risk for having a heart attack or stroke. Coronary artery disease is a condition where the blood flow to the heart is decreased.
Ticagrelor 90mg tablet is also used alone or together with aspirin to lessen the chance of stroke in patients with acute ischemic stroke or high-risk transient ischemic attack (TIA). Transient ischemic attack or mini-stroke is a condition where the blood supply to the brain is shortly blocked and lasts for a few minutes.
Indication : Ticagrelor 90mg tablet is used along with low-dose aspirin to help prevent heart attack and stroke in people with a history of heart disease, stroke, or at increased risk for heart disease or stroke (for example, due to diabetes, history of transient ischemic attack-TIA). It may also prevent blood clots after certain heart surgeries (such as stent placement).Ticagrelor 90mg tablet works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It keeps blood flowing smoothly in your body.
A heart attack or stroke may occur when a blood vessel in the heart or brain is blocked by a blood clot. Ticagrelor reduces the chance that a harmful blood clot will form by preventing certain cells in the blood from clumping together. This effect of ticagrelor may also increase the chance of serious bleeding in some people.
This medicine is available only with your doctors prescription.
Administration : Take this medicine at the same time every day. You may take it with or without food.
Storage : Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Side Effects : Back pain; bleeding gums; blurred vision; chest pain, tightness, or discomfort; confusion; cough; dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position;headache; increased menstrual flow or vaginal bleeding, unusual tiredness or weakness
Contraindications : Evidence has demonstrated fetal abnormalities or risks when used during pregnancy
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Safety Advice / Warnings : Tell your doctor right away if you have chest tightness, or difficult or trouble breathing when asleep or awake.
While you are using this medicine, if you have any kind of bleeding, it may take longer than usual to stop, especially if you hurt yourself. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Be careful when using sharp objects, including razors and fingernail clippers.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
References : Product Information: BRILINTA(TM) oral tablets, ticagrelor oral tablets. AstraZeneca LP (per manufacturer), Wilmington, DE, 2011.
Li J, Tang W, Storey RF, et al: Population pharmacokinetics of ticagrelor in patients with acute coronary syndromes. Int J Clin Pharmacol Ther 2016; 54(9):666-674.
PubMed Abstract: http://www.ncbi.nlm.nih.gov/...
Mechanism of Action : Ticagrelor, a cyclopentyltriazolopyrimidine, and its equipotent metabolite (AR-C124910XX) reversibly interact with the platelet P2Y(12) ADP-receptor, thereby preventing signal transduction and platelet activation and aggregation
Therapeutic : Platelet Aggregation Inhibitor