Amlodipine 5 Mg + Losartan Potassium 50 Mg + Hydrochlorothiazide 12.5 Mg

Swallow the tablet whole Do not break crush or chew it You may take this medicine with or without food.Take this medicine only as directed by your doctor. Do not use more of it do not use it more often, and do not use it for a longer time than your doctor ordered.

Store the medication at room temperature, away from moisture, heat, and direct sunlight.

Bloating or swelling of the face, arms, hands, lower legs, or feet; rapid weight gain tingling of the hands or feet unusual weight gain or loss Dizziness Headache Fatigue Hypotension (low blood pressure) Electrolyte disturbances (such as hypokalemia)

Avoid use of this drug during pregnancy, Evidence has demonstrated fetal abnormalities or risks when used during pregnancy and breastfeeding.

Using this medicine while you are pregnant can harm your unborn baby,especially in your second or third trimester. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. You may need to stop using this medicine. This medicine may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position. Make sure you know how you react to this medicine before you drive use machines, or do anything else that could be dangerous if you are dizzy If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. Check with your doctor right away if blurred vision difficulty with reading, eye pain, or any other change in vision occurs during or after treatment. This could be a sign of a serious eye problem. This medicine may affect blood sugar levels. Diabetic patients may notice a change in the results of blood or urine glucose tests. Talk to your doctor if you have any questions.

Product Information COZAAR(R) oral tablets, losartan potassium oral tablets. Merck Sharp & Dohme Corp. (per FDA), Whitehouse Station NJ 2015. Shahinfar S, Simpson RL, Carides AD, et al Safety of losartan in hypertensive patients with thiazide-induced hyperuricemia. Kidney Int 1999; 56:1879-1885. Amlodipine besylate [FDA Label]. New York, NY: Pfizer Labs 1987 [revised May 2011]. [Accessed 14 Mar. 2019] (online) Available from:External Link Product Information: Hydrochlorothiazide Aurovitas oral tablet, hydrochlorothiazide oral tablet. Aurovitas Spain, SAU (per AEMPS;Spain), Avda, De Burgos 28036 Madrid, Spain 2019.

Amlodipine: It is a calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle cells, resulting in vasodilation and a reduction in peripheral vascular resistance, thereby lowering blood pressure. Losartan Potassium: It is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to its receptors, leading to vasodilation and decreased aldosterone secretion resulting in decreased blood pressure. Hydrochlorothiazide: It is a thiazide diuretic that promotes diuresis by inhibiting sodium reabsorption in the kidneys, leading to decreased blood volume and subsequent reduction in blood pressure.

Anti hyperntiensive.