Product Details
CLOPIDOGREL 75 MG + ATORVASTATIN 10 MG
Introduction : Individuals who have experienced cardiovascular events such as heart attack (myocardial infarction) or stroke are often prescribed this combination medication to reduce the risk of recurrent events.
High-risk individuals, such as those with diabetes mellitus or multiple risk factors for cardiovascular disease, may be prescribed this combination medication to reduce their risk of future cardiovascular events.
The synergistic effects of clopidogrel and atorvastatin help address different aspects of cardiovascular risk, including platelet activation, cholesterol levels, and inflammation.
Clopidogrel 75mg reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood.
Atorvastatin 10mg works by blocking an enzyme that is needed by the body to make cholesterol, and this reduces the amount of cholesterol in the blood.
Indication : This combination of CLOPIDOGREL 75 MG + ATORVASTATIN 10 MGmedication is often prescribed for individuals at risk of cardiovascular events, particularly those with a history of:
Myocardial infarction (heart attack)
Stroke
Peripheral arterial disease
Coronary artery disease
Other conditions associated with increased risk of blood clots and atherosclerosis.
Administration : The typical dosage of Clopidogrel 75 mg + Atorvastatin 10 mg may vary depending on individual factors such as medical history, lipid profile, and cardiovascular risk.
It is usually taken orally, once daily, with or without food, as directed by a healthcare professional.
Storage : Store the medication at room temperature, away from moisture and heat. store under 30degree celsius
Side Effects : Common side effects of Clopidogrel may include:
Bleeding (including gastrointestinal bleeding)
Bruising
Rash
Itching
Common side effects of Atorvastatin may include:
Muscle pain or weakness
Liver enzyme abnormalities
Headache
Nausea
Contraindications : "Active liver disease, which may include unexplained persistent elevations
in hepatic transaminase levels
? Hypersensitivity to any component of this medication.
? Pregnancy .
? Lactation"
Safety Advice / Warnings : While you are using this medicine, if you have any kind of bleeding, it may take longer than usual to stop, especially if you hurt yourself. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Be careful when using sharp objects, including razors and fingernail clippers.
Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Avoid eating grapefruit or drinking grapefruit juice while using this medication
Do not drink large amounts of alcohol with atorvastatin. This could cause unwanted effects on the liver.
Call your doctor right away if you have dark-colored urine, fever, muscle cramps or spasms, muscle pain or stiffness, or unusual tiredness or weakness, this could be symptoms of kidney dysfunction
References : Product Information: LIPITOR(R) oral tablets, atorvastatin calcium oral tablets. Parke-Davis (Per FDA), New York, NY, 2014
Product Information: Atorvastatin Uxa oral tablet, atorvastatin calcium trihydrate oral tablet. Uxa Farma SA (per AEMPS;Spain), Avda. San Francisco Javier 24, 41018 Seville, Spain, 2019.
"Product Information: PLAVIX(R) oral tablets, clopidogrel bisulfate oral tablets. Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership (per FDA), Bridgewater, NJ, 2021.
Product Information: Zyllt oral tablet, clopidogrel oral tablet. KRKA, DD, Novo Mesto (per AEMPS;Spain), 2019.
Mechanism of Action : Clopidogrel (Antiplatelet): Irreversibly inhibits the P2Y12 receptor on platelets, preventing activation and aggregation of platelets, thus reducing the risk of blood clots.
Atorvastatin (Statins): Inhibits HMG-CoA reductase, which is involved in cholesterol synthesis in the liver. By lowering LDL cholesterol levels, atorvastatin helps reduce the risk of atherosclerosis and cardiovascular events.
Therapeutic : antihyperlipidemic