Olmesartan Medoxomil 40 Mg + Amlodipine 5 Mg + Hydrochlorothiazide 12.50 Mg

Swallow the tablet whole. Do not break, crush, or chew it. You may take this medicine with or without food. In addition to taking this medicine, treatment for your high blood pressure may include weight control and a change in the foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you.

Protect from moisture or light and store below 30 degrees Celsius (C).

Bloating or swelling of the face, arms, hands, lower legs, or feet; rapid weight gain; tingling of the hands or feet; unusual weight gain or loss electrolyte imbalances (such as low potassium levels), increased uric acid levels, and increased blood glucose levels.

Evidence has demonstrated fetal abnormalities or risks when used during pregnancy and breast feeding. consult with doctor immidaitely.

Using this medicine while you are pregnant can harm your unborn baby, especially in your second or third trimester. You may need to stop using this medicine. This medicine may cause dizziness, lightheadedness, or fainting, especially when you get up suddenly from a lying or sitting position. be cautious before you drive, use machines, or do anything else that could be dangerous if you are dizzy. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. Check with your doctor right away if you become sick while taking this medicine, especially if you have severe nausea, vomiting, or diarrhea that does not stop. These conditions may cause you to lose too much water and lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. This medicine may cause angina (chest pain). Check with your doctor right away if you are having chest pain or discomfort, fast or irregular heartbeat, nausea or vomiting, pain or discomfort in the arms, jaw, back, or neck, trouble breathing, or sweating. Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, trouble breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem. Check with your doctor right away if blurred vision, difficulty with reading, eye pain, or any other change in vision occurs during or after treatment. This could be a sign of a serious eye problem. This medicine may affect blood sugar levels. Diabetic patients may notice a change in the results of blood or urine glucose tests. Severe, chronic diarrhea with weight loss may develop months to years after taking this medicine.

Product Information: TRIBENZOR(R) oral tablets, olmesartan medoxomil amlodipine hydrochlorothiazide oral tablets. Daiichi Sankyo, Inc. (per FDA), Parsippany, NJ, 2014. Product Information: TRIBENZOR oral tablets, olmesartan medoxomil, amlodipine, hydrochlorothiazide oral tablets. Daiichi Sankyo Inc (per FDA), Parsippany, NJ, 2020.

Olmesartan medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby relaxing blood vessels and lowering blood pressure. Amlodipine is a calcium channel blocker (CCB) that works by relaxing the blood vessels, allowing blood to flow more easily and reducing blood pressure. Hydrochlorothiazide is a thiazide diuretic that works by increasing the excretion of sodium and water from the body, leading to reduced blood volume and decreased blood pressure.

Antihypertensive