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Ambroxol Hydrochloride 15mg + Guaiphenesin 100 Mg + Phenylephrine Hydrochloride 5 Mg + Chlorpheniramine Maleate 2 Mg + Menthol 1 Mg

Category: Medicine Product

Ambroxol Hydrochloride 15mg + Guaiphenesin 100 Mg + Phenylephrine Hydrochloride 5 Mg + Chlorpheniramine Maleate 2 Mg + Menthol 1 Mg

AMBROHIST-PLUS

Product Code: GMP0800

BOTTLE OF 100 ML

MRP: ~~₹ 117.00~~ (Inclusive of all taxes)

₹ 46.00 ( 60.68% Off )

Out Of Stock

Prescription required for purchase. Our doctors will review and verify it before confirming your order. Add to cart and submit your prescription with ease.

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Product Details

AMBROXOL HYDROCHLORIDE 15MG + GUAIPHENESIN 100 MG + PHENYLEPHRINE HYDROCHLORIDE 5 MG + CHLORPHENIRAMINE MALEATE 2 MG + MENTHOL 1 MG

Below are the product's comprehensive details, including its indications, administration, storage, side effects, safety advice, references, mechanism of action, and therapeutic uses.

This combination medication is commonly used for the symptomatic relief of cough and cold and to reduce associated respiratory and allergic symptoms. It may be prescribed for: Productive cough with thick mucus, Common cold,Allergic rhinitis, Upper respiratory tract infections, Nasal congestion, Throat irritation and chest congestion This medicine provides symptomatic relief and does not treat the underlying infection.

Take as directed by the physician. Shake the bottle well before use. Measure the dose using a proper measuring device. Can be taken with or without food.

Store below 25–30°C. Protect from light and moisture. Keep the bottle tightly closed. Keep out of reach of children.

Drowsiness or sedation Dizziness Dry mouth, nose, or throat Nausea or stomach upset

Do not use if: Known hypersensitivity to any component of the formulation Severe hypertension or significant heart disease Patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them Narrow-angle glaucoma Severe hyperthyroidism

May cause drowsiness; avoid driving or operating machinery. Use with caution in patients with: Hypertension Diabetes Thyroid disorders Prostatic enlargement Liver or kidney disease Avoid alcohol while taking this medicine. Not recommended in young children unless prescribed. Use during pregnancy and breastfeeding only if advised by a healthcare professional. Do not exceed the recommended dose.

FDA Drug Label – Phenylephrine, Chlorpheniramine, Guaifenesin combinations, DailyMed: https://dailymed.nlm.nih.gov Ambroxol Monograph – European Medicines Agency (EMA) Assessment Report Eccles R. Mechanisms of action of over-the-counter cold and cough medicines. Respiratory Physiology & Neurobiology. 2006;152(3):298–308. Brunton LL et al. Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 14th Edition. National Formulary of India (NFI), Latest Edition – Cough and Cold Preparations.

Ambroxol enhances mucociliary clearance by reducing mucus viscosity and stimulating surfactant production. Guaifenesin increases respiratory tract fluid secretion to facilitate expectoration. Phenylephrine acts as a selective α1-adrenergic agonist producing vasoconstriction of nasal mucosal vessels, thereby reducing congestion. Chlorpheniramine competitively blocks H1 receptors to inhibit histamine-mediated allergic symptoms, while menthol activates cold-sensitive TRPM8 receptors producing a soothing and cooling sensation.

Cough and Cold Preparation

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