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Pirfenidone 400 Mg Tablet
Medicine Product

Pirfenidone 400 Mg Tablet

Pirfenidone 400 mg Tablet is an antifibrotic medicine used for the treatment of idiopathic pulmonary fibrosis (IPF). It helps slow the progression of lung scarring and preserve lung function.

₹ 377.00 37.65% Off

MRP: ₹ 604.68  *Inclusive of all taxes

USP: Rs. 25.13 / TAB

Pack Size STRIP OF 15 TAB
Composition PIRFENIDONE 400 MG
Product Code GMP1287
Views 5100

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Product Details

Indication of Pirfenidone 400 Mg Tablet
Idiopathic pulmonary fibrosis (IPF) Slowing the progression of pulmonary fibrosis Preservation of lung function in patients with IPF
How To Use of Pirfenidone 400 Mg Tablet
Take the tablet exactly as prescribed by your physician. Take with food to reduce gastrointestinal side effects. Swallow the tablet whole with water. Follow the prescribed dose-escalation schedule if initiating therapy. Do not stop treatment without consulting your healthcare provider.
Storage of Pirfenidone 400 Mg Tablet
Store below 25°C in a cool and dry place.
Side Effects of Pirfenidone 400 Mg Tablet
Indigestion (dyspepsia) Loss of appetite Fatigue Headache
Contraindications of Pirfenidone 400 Mg Tablet
Hypersensitivity to pirfenidone or any component of the formulation. History of severe hypersensitivity reactions, including angioedema, associated with pirfenidone. Severe hepatic impairment or end-stage liver disease. Severe renal impairment or patients requiring dialysis, unless recommended by a specialist.
Safety Advice of Pirfenidone 400 Mg Tablet
Always take the medicine with food to improve tolerability. Avoid prolonged sun exposure and use sunscreen and protective clothing due to the risk of photosensitivity. Liver function tests should be performed before treatment and monitored regularly during therapy. Inform your doctor if you have liver disease, kidney disease, or are taking other medicines. Avoid smoking, as it can decrease pirfenidone exposure and reduce its effectiveness. Use during pregnancy and breastfeeding only if clearly indicated by your healthcare provider.
References of Pirfenidone 400 Mg Tablet
Raghu G, et al. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline: Treatment of Idiopathic Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. King TE Jr, et al. A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis. New England Journal of Medicine. Brunton LL, Hilal-Dandan R, Knollmann BC. Goodman & Gilman's The Pharmacological Basis of Therapeutics. British National Formulary (BNF). Pirfenidone Monograph.
Mechanism of Pirfenidone 400 Mg Tablet
Pirfenidone exhibits antifibrotic, anti-inflammatory, and antioxidant properties by inhibiting the synthesis and activity of profibrotic cytokines, particularly transforming growth factor-beta (TGF-β) and tumor necrosis factor-alpha (TNF-α). This suppresses fibroblast proliferation and collagen deposition, thereby slowing the progression of pulmonary fibrosis and preserving lung function.
Therapeutic of Pirfenidone 400 Mg Tablet
Antifibrotic Agent / Interstitial Lung Disease Therapy / Pulmonary Medicine / Anti-inflammatory Agent
Manufacturer of Pirfenidone 400 Mg Tablet

UNITED BIOCEUTICALS

Comparison

Brand Genericart Medicine
Medicine PIRFENEX 400 MG PIRFENIDONE 400 MG TABLET
Composition PIRFENIDONE 400 MG PIRFENIDONE 400 MG
Company CIPLA LTD GENERICART MEDICINE
Price ₹ 727.10 ₹ 377.00
You Save ₹ 350.10 (48.15% Less)

Disclaimer

At Genericart, our primary goal is to provide information that is thoroughly reviewed, accurate, and reliable. However, it is important to note that the content provided here should not be considered a substitute for professional medical advice. The information presented on our platform is intended for educational purposes only and may not cover all aspects of specific health conditions, medications, potential side effects, drug interactions, warnings, or alerts. We strongly encourage consulting with a qualified healthcare professional for advice and guidance regarding their health concerns and medication needs.

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