Product Details
PREGABALIN 75 MG
Introduction : Pregabalin 75mg capsule is used with other medicines to help control partial-onset seizures (convulsions) in the treatment of epilepsy in patients 1 month of age and older. This medicine will not cure epilepsy and will only work to control seizures for as long as you continue to take it.
Pregabalin 75mg capsule is also used for postherpetic neuralgia (pain that occurs after shingles) and pain caused by nerve damage from diabetes or a spinal cord injury.
Pregabalin 75mg capsule and oral liquid are also used to treat a condition called fibromyalgia (muscle pain and stiffness).
Pregabalin works in the central nervous system (CNS) to control seizures and pain. It is an anticonvulsant and neuropathic pain agent.
This medicine is available only with your doctors prescription.
Indication : Pregabalin 75 mg is commonly indicated for the treatment of several conditions, including:
Neuropathic pain associated with diabetic neuropathy
Neuropathic pain associated with postherpetic neuralgia
Neuropathic pain associated with spinal cord injury
Fibromyalgia
Partial-onset seizures in adults with epilepsy
Generalized anxiety disorder (GAD)
Administration : Pregabalin capsule or oral liquid may be taken with or without food.
Take the extended-release tablet after an evening meal. Swallow it whole. Do not crush, break, or chew it.
Storage : Store the medicine at room temperature, away from heat, moisture, and direct light.
Side Effects : Side effects may include constipation, dry mouth, diplopia, weight gain, edema , ataxia, and difficulty with concentration or attention, dizziness,
Contraindications : Avoid use of this drug during pregnancy. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy and breastfeeding
Safety Advice / Warnings : The use of alcohol or other medicines that affect the CNS with pregabalin may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping
This medicine may cause respiratory depression, a serious breathing problem that can be life-threatening, when used together with narcotic pain medicines. Check with your doctor right away
Pregabalin may cause blurred vision, double vision, clumsiness, unsteadiness, dizziness, drowsiness, or trouble with thinking. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. If these side effects are especially bothersome, check with your doctor.
Do not suddenly stop taking pregabalin without checking first with your doctor.
patient to avoid drinking alcohol
Extended-release tablets: If a dose is missed with the evening meal, instruct patient to take before bedtime after a snack or the following morning after a meal.
References : Product Information: LYRICA(R) CR oral extended-release tablets, pregabalin oral extended-release tablets. Viatris Specialty LLC (per FDA), Morgantown, WV, 2023.
Product Information: LYRICA(R) oral capsules, pregabalin oral capsules. Pfizer,Inc, New York, NY, 2007.
Feltner DE, Crockatt JG, Dubovsky SJ, et al: A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder. J Clin Psychopharmacol 2003; 23(3):240-249.
Mechanism of Action : Pregabalin is an anticonvulsant and analgesic medication that binds to calcium channels in the central nervous system. By binding to the ?2-? subunit of voltage-gated calcium channels, Pregabalin modulates the release of neurotransmitters, including glutamate, norepinephrine, and substance P, which are involved in pain signaling. This mechanism of action is believed to contribute to Pregabalins efficacy in managing neuropathic pain, epilepsy, and generalized anxiety disorder.
Therapeutic : Neuropathic Pain Agent