Product Details
CALCIUM CARBONATE 500 MG + CALCITRIOL 0.25 MCG + ZINC SULPHATE MONOHYDRATE 7.5 MG
Introduction : Calcium Carbonate 500 mg: A calcium supplement commonly used to prevent or treat calcium deficiency.
Calcitriol 0.25 mcg: The active form of vitamin D, which helps regulate calcium and phosphate metabolism.
Zinc Sulphate Monohydrate 7.5 mg: A form of zinc, an essential mineral involved in various physiological processes.
Indication : This combination medication is typically prescribed for:
Treatment of osteoporosis or osteomalacia (softening of the bones)
Management of calcium and vitamin D deficiency
Maintenance of bone health
Prevention of fractures
Administration : The typical dosage of Calcium Carbonate in combination with Calcitriol and Zinc Sulphate is usually one tablet taken orally once daily.
However, specific dosing instructions may vary based on individual factors such as age, medical condition, and the severity of the deficiency.
Storage : Store the medication at room temperature, away from moisture, heat, and direct sunlight.
Side Effects : While the combination of Calcium Carbonate, Calcitriol, and Zinc Sulphate is generally considered safe when taken as directed, some individuals may experience side effects. Common side effects may include:
Nausea
Vomiting
Constipation
Diarrhea
Stomach upset
Headache
Contraindications : Information regarding the use of this medicine during pregnancy is not available. Please consult your doctor.
Safety Advice / Warnings : This medicine may temporarily increase the calcium levels in your blood (hypercalcemia). Check with your doctor right away if you have stomach pain, confusion, depression, dry mouth, headache, incoherent speech, increased urination, loss of appetite, metallic taste, muscle weakness, unusual tiredness, nausea, vomiting, or weight loss.
References : Product Information: calcitriol solution, calcitriol solution. SICOR Pharmaceuticals, Inc, Irvine, CA, 2004.
Holick MF, Binkley NC, Bischoff-Ferrari HA, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.
Office of Dietary Supplements: Dietary Supplement Fact Sheet: Calcium. Office of Dietary Supplements, National Institutes of Health. Bethesda, MD. 2013.
Mechanism of Action : Calcitriol, an active form of vitamin D(3) or cholecalciferol, stimulates calcium transport in the intestines, its resorption in bones and tubular reabsorption in the kidney. It also suppresses the parathyroid hormone (PTH) secretion and synthesis
Calcium is essential for bone health and is involved in various physiological processes, including muscle function, nerve transmission, and blood clotting.
Calcitriol, the active form of vitamin D, facilitates the absorption of calcium and phosphorus in the intestines and helps regulate calcium levels in the blood.
Zinc is involved in bone mineralization and plays a role in immune function, wound healing, and DNA synthesis.
Therapeutic : Nutritional supplement