Product Details
GLUCOSAMINE SULPHATE POTASSIUM CHLORIDE 750 MG + METHYL SULFONYL METHANE 200 MG + DIACEREIN 50 MG
Introduction : This combination of Glucosamine Sulphate Potassium Cholride 750 Mg + Methyl Sulfonyl Methane 200 Mg + Diacerein 50 Mgmedication is typically prescribed for the management of osteoarthritis, a degenerative joint disease characterized by joint pain, stiffness, and reduced mobility. The components of this combination work synergistically to alleviate symptoms, reduce inflammation, and support joint health.
Indication : It is prescribed to treat osteoarthritis. It reduces pain and swelling by reducing inflammation. It also reduces friction in the joints to provide comfort during physical movements.
Administration : Typically, the recommended dose for adults is one tablet taken orally once or twice daily, with or without food.
Dosage adjustments may be necessary based on individual patient factors and response to treatment.
Storage : Store the medication at room temperature, away from moisture and heat. Keep it out of reach of children
Side Effects : Gastrointestinal discomfort (e.g., nausea, vomiting, diarrhea, constipation)
Headache
Dizziness
Skin rash or irritation
Safety Advice / Warnings : Consult a healthcare professional before using this combination medication during pregnancy or breastfeeding.
Use caution in patients with a history of gastrointestinal disorders or allergies to shellfish (glucosamine source).
Long-term use of Diacerein may be associated with hepatotoxicity (liver toxicity) and should be used with caution, particularly in patients with pre-existing liver conditions.
References : Fidelix TS, Macedo CR, Maxwell LJ, et al. Diacerein for osteoarthritis. Cochrane Database Syst Rev. 2014;
MedIndia. Glucosamine Sulfate Potassium Chloride.
Micromedex Medicine information database
Mechanism of Action : Glucosamine Sulphate: It is a naturally occurring compound found in the body, particularly in joint cartilage. Glucosamine Sulphate is involved in the synthesis of cartilage and other connective tissues. It helps to repair damaged cartilage, reduce inflammation, and improve joint function in osteoarthritis.
Methyl Sulfonyl Methane (MSM): It is an organic compound that contains sulfur, a vital component of joint cartilage and connective tissues. MSM helps to reduce inflammation, alleviate pain, and promote joint health by providing sulfur for the synthesis of collagen and other structural proteins.
Diacerein: It is a slow-acting anti-inflammatory agent that inhibits the production of pro-inflammatory cytokines, such as interleukin-1? (IL-1?). Diacerein helps to reduce inflammation, protect joint cartilage from degradation, and improve joint function in osteoarthritis.
Therapeutic : Joint health supplement