Glimepiride 4 Mg + Metformin Hydrochloride 1000 Mg Pr

Glimepiride 4mg Metformin Hydrochloride 1000mg PR (prolonged release) tablet is recommended for use in adults who have type 2 diabetes mellitus and cannot control their blood sugar levels with diet and exercise alone. It is not recommended for those patients who are suffering from ketoacidosis diabetes the extended-release formulation means that the medications are released gradually over an extended period, allowing for once-daily dosing. This may help in achieving a more consistent blood sugar control throughout the day. Metformin and Glimepiride is an antidiabetic agent that manages high blood sugar levels in type 2 diabetes patients. It reduces glucose absorption from the intestines, lowers liver glucose production, and improves insulin sensitivity. Metformin is recommended with dietary changes and exercise for better results.

Take the medication as prescribed, usually with meals. Regular monitoring of blood sugar levels is crucial. Report any unusual symptoms or side effects to your healthcare provider. Swallow the tablet or extended-release tablet whole with a full glass of water. Do not crush, break, or chew it. While taking the extended-release tablet, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

"Abdominal or stomach discomfort; cough general feeling of discomfort; muscle pain or cramping; painful or difficult urination; sleepiness Hypoglycemia, Nausea, Dizziness, Headache, Skin reactions.

Acute or chronic metabolic acidosis including diabetic ketoacidosis Severe renal impairment Avoid preganancy and lactation (breastfeeding) while consuming this medicines Too much glimepiride can cause low blood sugar (hypoglycemia) when it is used under certain conditions. Symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out).

Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines such as aspirin, and medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems. Hyperglycemia (high blood sugar) may occur if you do not take enough or skip a dose of your medicine, overeat or do not follow your meal plan, have a fever or infection, or do not exercise as much as usual. High blood sugar can be very serious and must be treated right away. It is important that you learn which symptoms you have in order to treat it quickly. Talk to your doctor about the best way to treat high blood sugar. Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy. Advise women of childbearing potential of fetal risk."" This medicine may cause dizziness, drowsiness, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert or able to think well.

Product Information: RIOMET ER(TM) oral extended-release suspension, metformin HCl oral extended-release suspension. Sun Pharmaceutical Industries Inc (per FDA), Cranbury, NJ, 2019. Product Information: GLUMETZA(R) oral extended-release tablets, metformin HCl oral extended-release tablets. Valeant Pharmaceuticals of North America (per FDA), Bridgewater, NJ, 2017. ""Product Information: AMARYL(R) oral tablets, glimepiride oral tablets . Sanofi-Aventis U.S. LLC (per FDA), Bridgewater, NJ, 2016. Badian M, Korn A, Lehr KH, et al: Determination of the absolute bioavailability of glimepiride (HOE 490), a new sulphonylurea. Int J Clin Pharmacol Ther Toxicol 1992; 30(11):481-482. Product Information: glimepiride oral tablets, glimepiride oral tablets. Accord Healthcare, Inc. (per DailyMed), Durham, NC, 2015.

Glimepiride works by Stimulates the pancreas to release insulin, thereby helping to lower blood sugar levels. and metformin works by Reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues, aiding in better glucose utilization.

Anti Diabetic