Rosuvastatin 40 Mg

You may take this medicine with or without food. Swallow the tablet whole. Do not break, crush, or chew it. To use the capsule: Swallow the capsule whole. Do not crush or chew it. If you have trouble swallowing, you may open it and mix the contents with 1 teaspoon of soft food. Take this mixture within 1 hour, without chewing.

Store the medicine at room temperature, away from heat, moisture, and direct light. Keep out of the reach of children.

Difficulty in moving, joint pain or swelling, muscle pain, cramps, spasms, or stiffness. Body aches or pain, congestion ,dry or sore throat,runny nose tender, swollen glands in the neck voice changes Tablet: Side effects may include headache, abdominal pain, asthenia, and nausea Capsule: side effects may include headache, nausea, myalgia, asthenia and constipation

Acute liver failure or decompensated cirrhosis Hypersensitivity to rosuvastatin or any component of the product .

If you need to take an antacid that contains aluminum and magnesium, take the antacid at least 2 hours after using rosuvastatin. Do not drink large amounts of alcohol while using rosuvastatin. This could cause side effects on the liver. Tell your doctor if you are pregnant or planning to become pregnant. Using this medicine while you are pregnant can harm your unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine if you have a major surgery, major injury, Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have unusual tiredness or a fever. Tablet: Advise patient not to take 2 doses within 12 hours of each other

Product Information: EZALLOR SPRINKLE(TM) oral capsules, rosuvastatin oral capsules. Sun Pharmaceutical Industries Inc (per FDA), Cranbury, NJ, 2023. Product Information: CRESTOR(R) oral tablets, rosuvastatin calcium oral tablets. AstraZeneca Pharmaceuticals LP (per FDA), Wilmington, DE, 2023. Micromedex drug Information database.

Rosuvastatin is an inhibitor of HMG-CoA reductase. This is the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol. Inhibition of HMG-CoA reductase by rosuvastatin accelerates the expression of LDL-receptors, followed by the uptake of LDL-C from blood to the liver, leading to a decrease in plasma LDL-C and total cholesterol. Sustained inhibition of cholesterol synthesis in the liver also decreases levels of very low density lipoproteins.

Statins