Product Details
TELMISARTAN 40 MG + HYDROCHLOROTHIAZIDE 12.5 MG
Introduction : This combination of Telmisartan 40 Mg + Hydrochlorothiazide 12.5 Mg tablet is indicated for the treatment of hypertension (high blood pressure) in patients whose blood pressure is not adequately controlled with monotherapy (single-drug therapy).
It may also be prescribed to reduce the risk of cardiovascular events in hypertensive patients.
Hydrochlorothiazide belongs to a class of drugs known as diuretics/"water pills." It works by causing you to make more urine. This helps your body get rid of extra salt and water.This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.
Indication : Telmisartan 40 Mg + Hydrochlorothiazide 12.5 Mg tablet is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains 2 medications: telmisartan and hydrochlorothiazide. Telmisartan belongs to a class of drugs called angiotensin receptor blockers (ARBs).
It works by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic). It increases the amount of urine you make, especially when you first start the medication. It also helps to relax the blood vessels so that blood can flow more easily.These medications are used together when 1 drug alone is not controlling your blood pressure.
Administration : Typically, one tablet is taken orally once daily, with or without food.
Its essential to follow the dosage instructions provided by your healthcare provider and not to exceed the prescribed dose.
It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate.
Storage : Store the medication at room temperature, away from moisture and heat.
Keep it out of reach of children
Mechanism of Action : Telmisartan: Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to its receptors, leading to vasodilation and lowering of blood pressure
Hydrochlorothiazide increases urine production by inhibiting the reabsorption of sodium and chloride ions in the kidneys, resulting in the removal of excess salt and water from the body and lowering blood volume and pressure.
Therapeutic : Cardiovascular Agent
Side Effects : Common side effects may include dizziness, headache, fatigue, electrolyte disturbances (such as low potassium levels), increased urination, and dehydration.
Contraindications : Evidence and/or expert consensus has demonstrated harmful infant effects when used during breastfeeding.
Avoid use of this drug during pregnancy and prescribe an alternative. Evidence has demonstrated fetal abnormalities or risks when used during pregnancy.
Safety Advice / Warnings : This medication may cause dizziness or lightheadedness, especially during the first few days of treatment or when standing up quickly from a sitting or lying position. Use caution when driving or operating machinery until you know how the medication affects you.
Avoid consuming alcohol while taking this medication, as it may potentiate the blood pressure-lowering effects and increase the risk of side effects.
Inform your healthcare provider about any other medications, supplements, or medical conditions you have before starting treatment with telmisartan/hydrochlorothiazide.
References : "Product Information: MICARDIS(R) oral tablets, telmisartan oral tablets. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, 2009
Product Information: Telmisartan. Boehringer Ingelheim, US, 98.
"Product Information: Hydrochlorothiazide Aurovitas oral tablet, hydrochlorothiazide oral tablet. Aurovitas Spain, SAU (per AEMPS;Spain), Avda, De Burgos, 28036 Madrid, Spain, 2019.
Product Information: Hydrochlorothiazide oral tablets, hydrochlorothiazide oral tablets. Accord Healthcare Inc (per DailyMed), Durham, NC, 2020.