Ambroxol Hydrochloride 15mg + Guaiphenesin 50 Mg + Phenylephrine Hydrochloride 5 Mg + Chlorpheniramine Maleate 2 Mg + Menthol 1 Mg

This medicine is commonly used for symptomatic relief of cough and cold. It may be prescribed for: Productive cough with mucus Chest congestion Common cold Runny nose and sneezing due to allergies Nasal congestion Throat irritation This medicine relieves symptoms but does not treat the underlying infection. Take under medical guidance.

Take as directed by your doctor. Shake well before use. Measure the dose using a calibrated measuring device. Can be taken with or without food. Dose is based on age and body weight (especially in children).

Store below 25–30°C. Protect from light and moisture. Keep tightly closed. Keep out of reach of children.

Common side effects include Drowsiness Dizziness Nausea or stomach upset Dry mouth

Use with caution in: Asthma Thyroid disorders Diabetes Elderly patients

May cause drowsiness; avoid activities requiring alertness if affected. Avoid alcohol while taking this medicine. it will enhance the eefect of alcohol. Do not exceed the recommended dose. If cough persists for more than 1–2 weeks, consult a doctor. Use in children only under medical supervision.

Eccles R. Mechanisms of cough and cold medicines. Respiratory Physiology & Neurobiology. 2006;152(3):298–308. Anon: Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; expectorant drug products for over-the-counter human use; final monograph.. Fed Regist 1989; 54(38):8494-509. Product Information: Fenesin. Dura Pharmaceuticals, US, 1993.

Ambroxol enhances mucociliary clearance by stimulating surfactant production and promoting lysosomal enzyme-mediated depolymerization of mucopolysaccharide fibers, thereby reducing sputum viscosity. Guaifenesin increases respiratory tract fluid secretion, facilitating expectoration. Phenylephrine is a selective α1-adrenergic receptor agonist that causes vasoconstriction in nasal mucosa, reducing edema and congestion. Chlorpheniramine competitively antagonizes H1 receptors, inhibiting histamine-mediated allergic responses, while menthol activates TRPM8 cold receptors producing a cooling sensation and mild antitussive effect.

Cough and Cold